6MS9
GDP-bound KRAS P34R mutant
Summary for 6MS9
Entry DOI | 10.2210/pdb6ms9/pdb |
Descriptor | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | gtpase kras hydrolysis, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 59193.49 |
Authors | Bera, A.K.,Westover, K.D. (deposition date: 2018-10-16, release date: 2020-04-15, Last modification date: 2023-10-11) |
Primary citation | Bera, A.K.,Lu, J.,Lu, C.,Li, L.,Gondi, S.,Yan, W.,Nelson, A.,Zhang, G.,Westover, K.D. GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R. Birth Defects Res, 112:708-717, 2020 Cited by PubMed: 32187889DOI: 10.1002/bdr2.1647 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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