6O36

Crystal structure of human KRAS P34R mutant in complex with GNP

Summary for 6O36

• Entry DOI: 10.2210/pdb6o36/pdb
• Descriptor: GTPase KRas, MAGNESIUM ION, PHOSPHATE ION, ... (5 entities in total)
• Functional Keywords: hydrolase, small gtpase, signal transduction, gnp binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 59342.44

Authors

Bera, A.K.,Westover, K.D. (deposition date: 2019-02-26, release date: 2020-02-26, Last modification date: 2023-10-11)

• Primary citation: Bera, A.K.,Lu, J.,Lu, C.,Li, L.,Gondi, S.,Yan, W.,Nelson, A.,Zhang, G.,Westover, K.D.; GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R.; Birth Defects Res, 112:708-717, 2020; PubMed: 32187889; DOI: 10.1002/bdr2.1647

Experimental method

X-RAY DIFFRACTION (2 Å)