8Q8O
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5O7P
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![BU of 5o7p by Molmil](/molmil-images/mine/5o7p) | HER3 in complex with Fab MF3178 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MF3178 FAB heavy chain, MF3178 FAB light chain, ... | Authors: | De Nardis, C, Gros, P. | Deposit date: | 2017-06-09 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4.5 Å) | Cite: | Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade. Cancer Cell, 33, 2018
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5O4G
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![BU of 5o4g by Molmil](/molmil-images/mine/5o4g) | HER2 in complex with Fab MF3958 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MF3958 FAB heavy chain, ... | Authors: | De Nardis, C, Gros, P. | Deposit date: | 2017-05-29 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade. Cancer Cell, 33, 2018
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5O4O
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![BU of 5o4o by Molmil](/molmil-images/mine/5o4o) | HER3 in complex with Fab MF3178 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MF3178 FAB heavy chain, ... | Authors: | De Nardis, C, Gros, P. | Deposit date: | 2017-05-30 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade. Cancer Cell, 33, 2018
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6HPV
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![BU of 6hpv by Molmil](/molmil-images/mine/6hpv) | Crystal structure of mouse fetuin-B | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Fetuin-B | Authors: | Fahrenkamp, D, Dietzel, E, de Sanctis, D, Jovine, L. | Deposit date: | 2018-09-22 | Release date: | 2019-02-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition. Iucrj, 6, 2019
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6N5A
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6E7H
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4C6R
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![BU of 4c6r by Molmil](/molmil-images/mine/4c6r) | Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RPS4 | Descriptor: | DISEASE RESISTANCE PROTEIN RPS4 | Authors: | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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4C6S
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![BU of 4c6s by Molmil](/molmil-images/mine/4c6s) | Crystal structure of the TIR domain from the Arabidopsis Thaliana disease resistance protein RRS1 | Descriptor: | GLYCEROL, PROBABLE WRKY TRANSCRIPTION FACTOR 52, SODIUM ION, ... | Authors: | Wan, L, Williams, S.J, Sohn, K.H, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.751 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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4C6T
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![BU of 4c6t by Molmil](/molmil-images/mine/4c6t) | Crystal structure of the RPS4 and RRS1 TIR domain heterodimer | Descriptor: | DISEASE RESISTANCE PROTEIN RPS4, MALONIC ACID, PROBABLE WRKY TRANSCRIPTION FACTOR 52 | Authors: | Williams, S.J, Sohn, K.H, Wan, L, Bernoux, M, Ma, Y, Segonzac, C, Ve, T, Sarris, P, Ericsson, D.J, Saucet, S.B, Zhang, X, Parker, J, Dodds, P.N, Jones, J.D.G, Kobe, B. | Deposit date: | 2013-09-19 | Release date: | 2014-05-28 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Basis for Assembly and Function of a Heterodimeric Plant Immune Receptor. Science, 344, 2014
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6PY9
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![BU of 6py9 by Molmil](/molmil-images/mine/6py9) | Crystal structure of red kidney bean purple acid phosphatase in complex with adenosine diphosphate metavanadate | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADP METAVANADATE, ... | Authors: | Feder, D, Schenk, G, Guddat, L.W, McGeary, R.P, Mitic, N, Furtado, A, Schulz, B.L, Henry, R.J, Schmidt, S. | Deposit date: | 2019-07-29 | Release date: | 2020-04-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural elements that modulate the substrate specificity of plant purple acid phosphatases: Avenues for improved phosphorus acquisition in crops. Plant Sci., 294, 2020
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6VJ7
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![BU of 6vj7 by Molmil](/molmil-images/mine/6vj7) | Crystal structure of red kidney bean purple acid phosphatase in complex with adenosine 5'-(beta,gamma imido)triphosphate | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Feder, D, Schenk, G, Guddat, L.W, McGeary, R.P, Mitic, N, Furtado, A, Schulz, B.L, Henry, R.J, Schmidt, S. | Deposit date: | 2020-01-15 | Release date: | 2020-04-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural elements that modulate the substrate specificity of plant purple acid phosphatases: Avenues for improved phosphorus acquisition in crops. Plant Sci., 294, 2020
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7MYX
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8DTN
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![BU of 8dtn by Molmil](/molmil-images/mine/8dtn) | The complex of nanobody 6101 with BCL11A ZF6 | Descriptor: | B-cell lymphoma/leukemia 11A, MAGNESIUM ION, Nanobody 6101, ... | Authors: | Yin, M, Tenglin, K, Zhai, L, Dassama, L.M, Orkin, S.H. | Deposit date: | 2022-07-26 | Release date: | 2023-02-01 | Method: | X-RAY DIFFRACTION (2.199 Å) | Cite: | Evolution of nanobodies specific for BCL11A. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DTU
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![BU of 8dtu by Molmil](/molmil-images/mine/8dtu) | The complex of nanobody 5344N74D with BCL11A ZF6. | Descriptor: | B-cell lymphoma/leukemia 11A, Nanobody 5344N74D, ZINC ION | Authors: | Yin, M, Tenglin, K, Zhai, L, Dassama, L.M, Orkin, S.H. | Deposit date: | 2022-07-26 | Release date: | 2023-02-01 | Method: | X-RAY DIFFRACTION (2.447 Å) | Cite: | Evolution of nanobodies specific for BCL11A. Proc.Natl.Acad.Sci.USA, 120, 2023
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7U20
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![BU of 7u20 by Molmil](/molmil-images/mine/7u20) | Crystal structure of human METTL1 and WDR4 complex | Descriptor: | SULFATE ION, tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 | Authors: | Li, J, Nowak, R.P, Fischer, E.S, Gregory, R. | Deposit date: | 2022-02-22 | Release date: | 2022-12-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4. Nature, 613, 2023
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8ET5
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![BU of 8et5 by Molmil](/molmil-images/mine/8et5) | Crystal structure of arabidopsis thaliana acetohydroxyacid synthase S653T mutant in complex with amidosulfuron | Descriptor: | 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ... | Authors: | Guddat, L.W, Cheng, Y. | Deposit date: | 2022-10-16 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase. J.Agric.Food Chem., 71, 2023
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8ET4
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![BU of 8et4 by Molmil](/molmil-images/mine/8et4) | Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron | Descriptor: | 2-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-2-[(1~{S})-1-(dioxidanyl)-1-oxidanyl-ethyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Acetolactate synthase, ... | Authors: | Guddat, L.W, Cheng, Y. | Deposit date: | 2022-10-16 | Release date: | 2023-03-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure of the Commercial Herbicide, Amidosulfuron, in Complex with Arabidopsis thaliana Acetohydroxyacid Synthase. J.Agric.Food Chem., 71, 2023
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8CTH
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![BU of 8cth by Molmil](/molmil-images/mine/8cth) | Cryo-EM structure of human METTL1-WDR4-tRNA(Phe) complex | Descriptor: | Phe-tRNA, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (guanine-N(7)-)-methyltransferase, ... | Authors: | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fishcer, E.S, Gregory, R.I. | Deposit date: | 2022-05-14 | Release date: | 2022-12-07 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4. Nature, 613, 2023
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8CTI
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![BU of 8cti by Molmil](/molmil-images/mine/8cti) | Cryo-EM structure of human METTL1-WDR4-tRNA(Val) complex | Descriptor: | tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4, tRNA-Val-TAC-2-1 | Authors: | Li, J, Wang, L, Fontana, P, Hunkeler, M, Roy-Burman, S.S, Wu, H, Fischer, E.S, Gregory, R.I. | Deposit date: | 2022-05-14 | Release date: | 2022-12-07 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis of regulated m 7 G tRNA modification by METTL1-WDR4. Nature, 613, 2023
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7K9R
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![BU of 7k9r by Molmil](/molmil-images/mine/7k9r) | Cryptococcus neoformans Hsp90 nucleotide binding domain | Descriptor: | CHLORIDE ION, Hsp90-like protein | Authors: | Kuntz, D.A, Kenney, T, Prive, G.G. | Deposit date: | 2020-09-29 | Release date: | 2021-01-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity. J.Med.Chem., 64, 2021
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8P66
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5K6R
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![BU of 5k6r by Molmil](/molmil-images/mine/5k6r) | Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, ... | Authors: | Garcia, M.D, Lonhienne, T, Guddat, L.W. | Deposit date: | 2016-05-25 | Release date: | 2017-02-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.734 Å) | Cite: | Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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8R06
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![BU of 8r06 by Molmil](/molmil-images/mine/8r06) | CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLANOLYTICUM GH116 BETA-GLUCOSIDASE WITH A COVALENTLY BOUND CYCLOPHELLITOL AZIRIDINE | Descriptor: | (1~{R},2~{S},3~{S},4~{S},5~{R},6~{R})-5-azanyl-6-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol, CALCIUM ION, CHLORIDE ION, ... | Authors: | Offen, W.A, Davies, G.J, Breen, I.Z. | Deposit date: | 2023-10-30 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | CRYSTAL STRUCTURE OF THERMOANAEROBACTERIUM XYLOLYTICUM GH116 BETA-GLUCOSIDASE WITH A COVALENTLY BOUND CYCLOPHELLITOL AZIRIDINE JACS, 40, 2017
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5K6T
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![BU of 5k6t by Molmil](/molmil-images/mine/5k6t) | Crystal structure of Arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, Acetolactate synthase, ... | Authors: | Garcia, M.D, Lonhienne, T, Guddat, L.W. | Deposit date: | 2016-05-25 | Release date: | 2017-02-08 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.763 Å) | Cite: | Comprehensive understanding of acetohydroxyacid synthase inhibition by different herbicide families. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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