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8DTN

The complex of nanobody 6101 with BCL11A ZF6

Summary for 8DTN
Entry DOI10.2210/pdb8dtn/pdb
DescriptorNanobody 6101, B-cell lymphoma/leukemia 11A, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordsnanobody, bcl11a, transcription factor, zinc finger domain, protein degradation, gamma globin, sickle cells, dna binding protein
Biological sourceLama glama
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Total number of polymer chains8
Total formula weight66550.45
Authors
Yin, M.,Tenglin, K.,Zhai, L.,Dassama, L.M.,Orkin, S.H. (deposition date: 2022-07-26, release date: 2023-02-01)
Primary citationYin, M.,Izadi, M.,Tenglin, K.,Viennet, T.,Zhai, L.,Zheng, G.,Arthanari, H.,Dassama, L.M.K.,Orkin, S.H.
Evolution of nanobodies specific for BCL11A.
Proc.Natl.Acad.Sci.USA, 120:e2218959120-e2218959120, 2023
Cited by
PubMed: 36626555
DOI: 10.1073/pnas.2218959120
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.199 Å)
Structure validation

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