8DTU
The complex of nanobody 5344N74D with BCL11A ZF6.
Summary for 8DTU
| Entry DOI | 10.2210/pdb8dtu/pdb |
| Related | 8DTN |
| Descriptor | Nanobody 5344N74D, B-cell lymphoma/leukemia 11A, ZINC ION, ... (5 entities in total) |
| Functional Keywords | nanobody, bcl11a, transcription factor, zinc finger domain, protein degradation, gamma globin, sickle cells, dna binding protein |
| Biological source | Lama glama More |
| Total number of polymer chains | 3 |
| Total formula weight | 16416.36 |
| Authors | Yin, M.,Tenglin, K.,Zhai, L.,Dassama, L.M.,Orkin, S.H. (deposition date: 2022-07-26, release date: 2023-02-01) |
| Primary citation | Yin, M.,Izadi, M.,Tenglin, K.,Viennet, T.,Zhai, L.,Zheng, G.,Arthanari, H.,Dassama, L.M.K.,Orkin, S.H. Evolution of nanobodies specific for BCL11A. Proc.Natl.Acad.Sci.USA, 120:e2218959120-e2218959120, 2023 Cited by PubMed: 36626555DOI: 10.1073/pnas.2218959120 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.447 Å) |
Structure validation
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