3NYN
| Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with Sangivamycin | Descriptor: | (R,R)-2,3-BUTANEDIOL, G protein-coupled receptor kinase 6, SANGIVAMYCIN, ... | Authors: | Tesmer, J.J.G, Singh, P. | Deposit date: | 2010-07-15 | Release date: | 2010-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Molecular basis for activation of G protein-coupled receptor kinases. Embo J., 29, 2010
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3NYO
| Crystal Structure of G Protein-Coupled Receptor Kinase 6 in Complex with AMP | Descriptor: | (R,R)-2,3-BUTANEDIOL, ADENOSINE MONOPHOSPHATE, G protein-coupled receptor kinase 6, ... | Authors: | Tesmer, J.J.G, Singh, P. | Deposit date: | 2010-07-15 | Release date: | 2010-09-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.92 Å) | Cite: | Molecular basis for activation of G protein-coupled receptor kinases. Embo J., 29, 2010
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2BCJ
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1TXD
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4WBO
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9ABP
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8ABP
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1BAP
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1X86
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1ZCB
| Crystal structure of G alpha 13 in complex with GDP | Descriptor: | G alpha i/13, GUANOSINE-5'-DIPHOSPHATE | Authors: | Nance, M.R, Tesmer, J.J.G. | Deposit date: | 2005-04-11 | Release date: | 2005-11-15 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins. Biochemistry, 45, 2006
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2RGN
| Crystal Structure of p63RhoGEF complex with Galpha-q and RhoA | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1,Guanine nucleotide-binding protein G(q) subunit alpha, MAGNESIUM ION, ... | Authors: | Shankaranarayanan, A, Nance, M.R, Tesmer, J.J.G. | Deposit date: | 2007-10-04 | Release date: | 2008-01-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Structure of Galphaq-p63RhoGEF-RhoA complex reveals a pathway for the activation of RhoA by GPCRs. Science, 318, 2007
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7ABP
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6MVD
| Crystal structure of Lecithin:cholesterol acyltransferase (LCAT) in complex with isopropyl dodec-11-enylfluorophosphonate (IDFP) and a small molecule activator | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-{4-[(4R)-4-hydroxy-6-oxo-4-(trifluoromethyl)-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-b]pyridin-3-yl]piperidin-1-yl}-4-(trifluoromethyl)pyridine-3-carbonitrile, NICKEL (II) ION, ... | Authors: | Manthei, K.A, Chang, L, Tesmer, J.J.G. | Deposit date: | 2018-10-25 | Release date: | 2018-12-05 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular basis for activation of lecithin:cholesterol acyltransferase by a compound that increases HDL cholesterol. Elife, 7, 2018
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4L9I
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4MK0
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4GNK
| Crystal structure of Galphaq in complex with full-length human PLCbeta3 | Descriptor: | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Lyon, A.M, Tesmer, J.J.G. | Deposit date: | 2012-08-17 | Release date: | 2013-02-06 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Full-length G alpha (q)-phospholipase C-beta 3 structure reveals interfaces of the C-terminal coiled-coil domain. Nat.Struct.Mol.Biol., 20, 2013
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2I1K
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2I1J
| Moesin from Spodoptera frugiperda at 2.1 angstroms resolution | Descriptor: | CHLORIDE ION, GLYCEROL, Moesin, ... | Authors: | Li, Q, Nance, M.R, Tesmer, J.J.G. | Deposit date: | 2006-08-14 | Release date: | 2006-12-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Self-masking in an Intact ERM-merlin Protein: An Active Role for the Central alpha-Helical Domain. J.Mol.Biol., 365, 2007
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1ZCA
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3QR0
| Crystal Structure of S. officinalis PLC21 | Descriptor: | CALCIUM ION, GLYCEROL, phospholipase C-beta (PLC-beta) | Authors: | Lyon, A.M, Northup, J.K, Tesmer, J.J.G. | Deposit date: | 2011-02-16 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation. Nat.Struct.Mol.Biol., 18, 2011
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3QR1
| Crystal Structure of L. pealei PLC21 | Descriptor: | CALCIUM ION, PHOSPHOLIPASE C-BETA (PLC-BETA) | Authors: | Lyon, A.M, Suddala, K.C, Northup, J.K, Tesmer, J.J.G. | Deposit date: | 2011-02-16 | Release date: | 2011-08-10 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation. Nat.Struct.Mol.Biol., 18, 2011
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4BEZ
| Night blindness causing G90D rhodopsin in the active conformation | Descriptor: | ACETATE ION, PALMITIC ACID, RHODOPSIN, ... | Authors: | Singhal, A, Ostermaier, M.K, Vishnivetskiy, S.A, Panneels, V, Homan, K.T, Tesmer, J.J.G, Veprintsev, D, Deupi, X, Gurevich, V.V, Schertler, G.F.X, Standfuss, J. | Deposit date: | 2013-03-12 | Release date: | 2013-04-24 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin. Embo Rep., 14, 2013
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4BEY
| Night blindness causing G90D rhodopsin in complex with GaCT2 peptide | Descriptor: | ACETATE ION, Guanine nucleotide-binding protein G(t) subunit alpha-1, PALMITIC ACID, ... | Authors: | Singhal, A, Ostermaier, M.K, Vishnivetskiy, S.A, Panneels, V, Homan, K.T, Tesmer, J.J.G, Veprintsev, D, Deupi, X, Gurevich, V.V, Schertler, G.F.X, Standfuss, J. | Deposit date: | 2013-03-12 | Release date: | 2013-05-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Insights Into Congenital Stationary Night Blindness Based on the Structure of G90D Rhodopsin. Embo Rep., 14, 2013
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2ACX
| Crystal Structure of G protein coupled receptor kinase 6 bound to AMPPNP | Descriptor: | G protein-coupled receptor kinase 6, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Lodowski, D.T, Tesmer, V.M, Benovic, J.L, Tesmer, J.J. | Deposit date: | 2005-07-19 | Release date: | 2006-04-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The Structure of G Protein-coupled Receptor Kinase (GRK)-6 Defines a Second Lineage of GRKs. J.Biol.Chem., 281, 2006
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3V5W
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