4WBO

Bovine G Protein Coupled Receptor Kinase 1 in Complex with Amlexanox

Summary for 4WBO

Entry DOI	10.2210/pdb4wbo/pdb
Related	4L9I
Descriptor	Rhodopsin kinase, 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	g-protein-coupled receptor kinase 1, amlexanox, phosphorylation, protein conformation, protein kinase inhibitors, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Bos taurus (Bovine)
Total number of polymer chains	4
Total formula weight	246197.84
Authors	Homan, K.T.,Tesmer, J.J.G. (deposition date: 2014-09-03, release date: 2014-11-05, Last modification date: 2023-12-27)
Primary citation	Homan, K.T.,Wu, E.,Cannavo, A.,Koch, W.J.,Tesmer, J.J. Identification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor. Molecules, 19:16937-16949, 2014 Cited by PubMed: 25340299 DOI: 10.3390/molecules191016937 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.81 Å)

Structure validation