4WBO
Bovine G Protein Coupled Receptor Kinase 1 in Complex with Amlexanox
Summary for 4WBO
Entry DOI | 10.2210/pdb4wbo/pdb |
Related | 4L9I |
Descriptor | Rhodopsin kinase, 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | g-protein-coupled receptor kinase 1, amlexanox, phosphorylation, protein conformation, protein kinase inhibitors, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 4 |
Total formula weight | 246197.84 |
Authors | Homan, K.T.,Tesmer, J.J.G. (deposition date: 2014-09-03, release date: 2014-11-05, Last modification date: 2023-12-27) |
Primary citation | Homan, K.T.,Wu, E.,Cannavo, A.,Koch, W.J.,Tesmer, J.J. Identification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor. Molecules, 19:16937-16949, 2014 Cited by PubMed: 25340299DOI: 10.3390/molecules191016937 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.81 Å) |
Structure validation
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