2BCJ
Crystal Structure of G Protein-Coupled Receptor Kinase 2 in Complex with Galpha-q and Gbetagamma Subunits
Summary for 2BCJ
Entry DOI | 10.2210/pdb2bcj/pdb |
Related | 1OMW 1YM7 |
Descriptor | G-protein-coupled receptor kinase 2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (8 entities in total) |
Functional Keywords | peripheral membrane complex, protein kinase, rgs domain, wd40 protein, heterotrimeric g protein, transferase-hydrolase complex, transferase/hydrolase |
Biological source | Bos taurus (Bovine) More |
Cellular location | Cytoplasm : P21146 Cell membrane ; Lipid-anchor ; Cytoplasmic side : P63212 Nucleus : P21279 |
Total number of polymer chains | 4 |
Total formula weight | 166776.15 |
Authors | Tesmer, J.J.G. (deposition date: 2005-10-19, release date: 2005-12-20, Last modification date: 2023-08-23) |
Primary citation | Tesmer, V.M.,Kawano, T.,Shankaranarayanan, A.,Kozasa, T.,Tesmer, J.J.G. Snapshot of Activated G Proteins at the Membrane: The Gq-GRK2-G Complex Science, 310:1686-1690, 2005 Cited by PubMed: 16339447DOI: 10.1126/science.1118890 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.061 Å) |
Structure validation
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