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9B8U
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BU of 9b8u by Molmil
Crystal structure of CRX-Ret4 oligonucleotide complex
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Cone-rod homeobox protein, ...
著者Srivastava, D, Artemyev, N.O.
登録日2024-04-01
公開日2024-07-31
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular basis of CRX/DNA recognition and stoichiometry at the Ret4 response element.
Structure, 32, 2024
8EOB
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BU of 8eob by Molmil
Cryo-EM structure of human HSP90B in the closed state
分子名称: Heat shock protein HSP 90-beta, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
著者Srivastava, D, Artemyev, N.O.
登録日2022-10-02
公開日2023-01-25
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1.
Structure, 31, 2023
8EOA
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BU of 8eoa by Molmil
Cryo-EM structure of human HSP90B-AIPL1 complex
分子名称: Aryl-hydrocarbon-interacting protein-like 1, Heat shock protein HSP 90-beta, MAGNESIUM ION, ...
著者Srivastava, D, Artemyev, N.O.
登録日2022-10-02
公開日2023-01-25
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Unique interface and dynamics of the complex of HSP90 with a specialized cochaperone AIPL1.
Structure, 31, 2023
6N85
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BU of 6n85 by Molmil
Resistance to inhibitors of cholinesterase 8A (Ric8A) protein in complex with MBP-tagged transducin-alpha residues 327-350
分子名称: Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, Synembryn-A, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6NUB
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BU of 6nub by Molmil
Pyruvate Kinase M2 Mutant - S437Y in Complex with L-serine
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ...
著者Srivastava, D, Nandi, S, Dey, M.
登録日2019-01-31
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 58, 2019
6NU1
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BU of 6nu1 by Molmil
Crystal Structure of Human PKM2 in Complex with L-cysteine
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, CYSTEINE, MAGNESIUM ION, ...
著者Srivastava, D, Nandi, S, Dey, M.
登録日2019-01-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 58, 2019
6NU5
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Pyruvate Kinase M2 Mutant - S437Y in Complex with L-cysteine
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ...
著者Srivastava, D, Nandi, S, Dey, M.
登録日2019-01-30
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Mechanistic and Structural Insights into Cysteine-Mediated Inhibition of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 58, 2019
6N84
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BU of 6n84 by Molmil
MBP-fusion protein of transducin-alpha residues 327-350
分子名称: Maltose/maltodextrin-binding periplasmic protein,Guanine nucleotide-binding protein G(t) subunit alpha-2, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6N86
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BU of 6n86 by Molmil
Resistance to inhibitors of cholinesterase 8A (Ric8A) protein
分子名称: Synembryn-A
著者Srivastava, D, Gakhar, L, Artemyev, N.O.
登録日2018-11-28
公開日2019-07-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural underpinnings of Ric8A function as a G-protein alpha-subunit chaperone and guanine-nucleotide exchange factor.
Nat Commun, 10, 2019
6B6U
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BU of 6b6u by Molmil
Pyruvate Kinase M2 mutant - S437Y
分子名称: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Srivastava, D, Dey, M.
登録日2017-10-03
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2.
Biochemistry, 56, 2017
7UMO
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BU of 7umo by Molmil
Structure of Unc119-inhibitor complex.
分子名称: (3s,5s,7s)-N-(4,5-dichloropyridin-2-yl)adamantane-1-carboxamide, GLYCEROL, Protein unc-119 homolog A
著者Srivastava, D, Sebag, J.A, Artemyev, N.O.
登録日2022-04-07
公開日2023-07-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insulin sensitization by small molecules enhancing GLUT4 translocation.
Cell Chem Biol, 30, 2023
3V9K
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BU of 3v9k by Molmil
Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with the product glutamate
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, GLUTAMIC ACID, ...
著者Tanner, J.J, Srivastava, D.
登録日2011-12-27
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献The Three-Dimensional Structural Basis of Type II Hyperprolinemia.
J.Mol.Biol., 420, 2012
3V9J
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BU of 3v9j by Molmil
Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with sulfate ion
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, GLYCEROL, ...
著者Tanner, J.J, Srivastava, D.
登録日2011-12-27
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献The Three-Dimensional Structural Basis of Type II Hyperprolinemia.
J.Mol.Biol., 420, 2012
3V9L
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BU of 3v9l by Molmil
Crystal structure of mouse 1-pyrroline-5-carboxylate dehydrogenase complexed with NAD+
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, GLYCEROL, ...
著者Tanner, J.J, Srivastava, D.
登録日2011-12-27
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献The Three-Dimensional Structural Basis of Type II Hyperprolinemia.
J.Mol.Biol., 420, 2012
3V9G
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BU of 3v9g by Molmil
Crystal structure of human 1-pyrroline-5-carboxylate dehydrogenase
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
著者Tanner, J.J, Srivastava, D.
登録日2011-12-27
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The Three-Dimensional Structural Basis of Type II Hyperprolinemia.
J.Mol.Biol., 420, 2012
6WP3
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BU of 6wp3 by Molmil
Pyruvate Kinase M2 Mutant-K433Q
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Nandi, S, Razzaghi, M, Srivastava, D, Dey, M.
登録日2020-04-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
J.Biol.Chem., 295, 2020
6WP5
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BU of 6wp5 by Molmil
Pyruvate Kinase M2 mutant-S37D
分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, MAGNESIUM ION, ...
著者Nandi, S, Razzaghi, M, Srivastava, D, Dey, M.
登録日2020-04-26
公開日2020-09-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
J.Biol.Chem., 295, 2020
6WP6
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BU of 6wp6 by Molmil
Pyruvate Kinase M2 mutant-S37E K433E
分子名称: GLYCEROL, MAGNESIUM ION, NITRATE ION, ...
著者Nandi, S, Razzaghi, M, Srivastava, D, Dey, M.
登録日2020-04-26
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
J.Biol.Chem., 295, 2020
6WP4
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BU of 6wp4 by Molmil
Pyruvate Kinase M2 mutant-S37E
分子名称: CHLORIDE ION, GLYCEROL, MAGNESIUM ION, ...
著者Nandi, S, Razzaghi, M, Srivastava, D, Dey, M.
登録日2020-04-26
公開日2020-09-30
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.
J.Biol.Chem., 295, 2020
3ITG
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BU of 3itg by Molmil
Structure the proline utilization A proline dehydrogenase domain (PutA86-630) inactivated with N-propargylglycine
分子名称: Bifunctional protein putA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
著者Tanner, J.J.
登録日2009-08-28
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.
Biochemistry, 49, 2010
3HAZ
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BU of 3haz by Molmil
Crystal structure of bifunctional proline utilization A (PutA) protein
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Tanner, J.J.
登録日2009-05-03
公開日2010-02-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum
Proc.Natl.Acad.Sci.USA, 107, 2010
3V9H
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BU of 3v9h by Molmil
Crystal structure of human 1-pyrroline-5-carboxylate dehydrogenase mutant S352A
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, SULFATE ION
著者Tanner, J.J, Singh, R.K.
登録日2011-12-27
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Three-Dimensional Structural Basis of Type II Hyperprolinemia.
J.Mol.Biol., 420, 2012
3V9I
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BU of 3v9i by Molmil
Crystal structure of human 1-pyrroline-5-carboxylate dehydrogenase mutant S352L
分子名称: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
著者Tanner, J.J, Singh, R.K.
登録日2011-12-27
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献The Three-Dimensional Structural Basis of Type II Hyperprolinemia.
J.Mol.Biol., 420, 2012
8G0M
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BU of 8g0m by Molmil
Structure of complex between TV6.6 and CD98hc ECD
分子名称: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, TETRAETHYLENE GLYCOL, ...
著者Kariolis, M.S, Lexa, K, Liau, N.P.D, Srivastava, D, Tran, H, Wells, R.C.
登録日2023-01-31
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献CD98hc is a target for brain delivery of biotherapeutics.
Nat Commun, 14, 2023
4E3X
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BU of 4e3x by Molmil
Crystal Structure of Mus musculus 1-pyrroline-5-carboxylate dehydrogenase cryoprotected in proline
分子名称: 3,6,9,12,15,18-HEXAOXAICOSANE, Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial, ...
著者Tanner, J.J, Pemberton, T.A.
登録日2012-03-10
公開日2012-07-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Proline: Mother Nature's cryoprotectant applied to protein crystallography.
Acta Crystallogr.,Sect.D, 68, 2012

 

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