6B6U

Pyruvate Kinase M2 mutant - S437Y

Summary for 6B6U

Entry DOI	10.2210/pdb6b6u/pdb
Descriptor	Pyruvate kinase PKM, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (11 entities in total)
Functional Keywords	glycolysis, gene regulation, phosphotransferase, transferase
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P14618
Total number of polymer chains	2
Total formula weight	116495.61
Authors	Srivastava, D.,Dey, M. (deposition date: 2017-10-03, release date: 2017-12-20, Last modification date: 2023-10-04)
Primary citation	Srivastava, D.,Razzaghi, M.,Henzl, M.T.,Dey, M. Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2. Biochemistry, 56:6517-6520, 2017 Cited by PubMed: 29182273 DOI: 10.1021/acs.biochem.7b01013 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation