6WP4

Pyruvate Kinase M2 mutant-S37E

Summary for 6WP4

Entry DOI	10.2210/pdb6wp4/pdb
Descriptor	Pyruvate kinase PKM, PHOSPHATE ION, MAGNESIUM ION, ... (8 entities in total)
Functional Keywords	glycolysis, gene regulation, phosphotransferase, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	4
Total formula weight	243610.56
Authors	Nandi, S.,Razzaghi, M.,Srivastava, D.,Dey, M. (deposition date: 2020-04-26, release date: 2020-09-30, Last modification date: 2023-10-18)
Primary citation	Nandi, S.,Razzaghi, M.,Srivastava, D.,Dey, M. Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation. J.Biol.Chem., 295:17425-17440, 2020 Cited by PubMed: 33453989 DOI: 10.1074/jbc.RA120.015800 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation