3ITG

Structure the proline utilization A proline dehydrogenase domain (PutA86-630) inactivated with N-propargylglycine

Summary for 3ITG

• Entry DOI: 10.2210/pdb3itg/pdb
• Related: 1tiw 2ekg
• Descriptor: Bifunctional protein putA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE (3 entities in total)
• Functional Keywords: proline utilization a, puta, flavoenzyme, mechanism-based inactivation, dna-binding, fad, flavoprotein, multifunctional enzyme, nad, oxidoreductase, proline metabolism, repressor, transcription, transcription regulation
• Biological source: Escherichia coli K-12
• Total number of polymer chains: 2
• Total formula weight: 136552.44

Authors

Tanner, J.J. (deposition date: 2009-08-28, release date: 2010-01-12, Last modification date: 2023-09-06)

• Primary citation: Srivastava, D.,Zhu, W.,Johnson, W.H.,Whitman, C.P.,Becker, D.F.,Tanner, J.J.; The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction.; Biochemistry, 49:560-569, 2010; PubMed: 19994913; DOI: 10.1021/bi901717s

Experimental method

X-RAY DIFFRACTION (2.15 Å)