6WP6

Pyruvate Kinase M2 mutant-S37E K433E

Summary for 6WP6

• Entry DOI: 10.2210/pdb6wp6/pdb
• Descriptor: Pyruvate kinase PKM, NITRATE ION, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: glycolysis, gene regulation, phosphotransferase, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 120659.06

Authors

Nandi, S.,Razzaghi, M.,Srivastava, D.,Dey, M. (deposition date: 2020-04-26, release date: 2020-10-07, Last modification date: 2023-10-18)

• Primary citation: Nandi, S.,Razzaghi, M.,Srivastava, D.,Dey, M.; Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation.; J.Biol.Chem., 295:17425-17440, 2020; PubMed: 33453989; DOI: 10.1074/jbc.RA120.015800

Experimental method

X-RAY DIFFRACTION (2.45 Å)