7UMO
Structure of Unc119-inhibitor complex.
Summary for 7UMO
| Entry DOI | 10.2210/pdb7umo/pdb |
| Descriptor | Protein unc-119 homolog A, (3s,5s,7s)-N-(4,5-dichloropyridin-2-yl)adamantane-1-carboxamide, GLYCEROL, ... (4 entities in total) |
| Functional Keywords | unc119, inhibitor, transport protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 6 |
| Total formula weight | 140377.81 |
| Authors | Srivastava, D.,Sebag, J.A.,Artemyev, N.O. (deposition date: 2022-04-07, release date: 2023-07-26, Last modification date: 2023-08-30) |
| Primary citation | Yin, T.C.,Van Vranken, J.G.,Srivastava, D.,Mittal, A.,Buscaglia, P.,Moore, A.E.,Verdinez, J.A.,Graham, A.E.,Walsh, S.A.,Acevedo, M.A.,Kerns, R.J.,Artemyev, N.O.,Gygi, S.P.,Sebag, J.A. Insulin sensitization by small molecules enhancing GLUT4 translocation. Cell Chem Biol, 30:933-942.e6, 2023 Cited by PubMed: 37453421DOI: 10.1016/j.chembiol.2023.06.012 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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