5A5G
 
 | | Crystal structure of FTHFS2 from T.acetoxydans Re1 | | 分子名称: | DI(HYDROXYETHYL)ETHER, FORMATE--TETRAHYDROFOLATE LIGASE, GLYCEROL, ... | | 著者 | Bergdahl, R, Jacobson, F, Muller, B, Mikkelsen, N, Schurer, A, Sandgren, M. | | 登録日 | 2015-06-17 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization, Crystallization and Three- Dimensional Structures of Formyltetrahydrofolate Synthetase (Fthfs) from the Syntrophic Acetate Oxidising Bacterium Tepidanaerobacter Acetatoxydans Re1
To be Published
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1KKS
 | | Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression | | 分子名称: | 5'-R(*GP*GP*AP*AP*GP*GP*CP*CP*CP*UP*UP*UP*UP*CP*AP*GP*GP*GP*CP*CP*AP*CP*CP*C)-3' | | 著者 | Zanier, K, Luyten, I, Crombie, C, Muller, B, Schuemperli, D, Linge, J.P, Nilges, M, Sattler, M. | | 登録日 | 2001-12-10 | | 公開日 | 2002-03-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression.
RNA, 8, 2002
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5A4J
 | | Crystal structure of FTHFS1 from T.acetoxydans Re1 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, D(-)-TARTARIC ACID, ... | | 著者 | Bergdahl, R, Jacobson, F, Muller, B, Mikkelsen, N, Schurer, A, Sandgren, M. | | 登録日 | 2015-06-10 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Characterization, Crystallization and Three- Dimensional Structures of Formyltetrahydrofolate Synthetase (Fthfs) from the Syntrophic Acetate Oxidising Bacterium Tepidanaerobacter Acetatoxydans Re1
To be Published
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7TBM
 | | Composite structure of the dilated human nuclear pore complex (NPC) generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | | 分子名称: | DDX19, NUP107 CTD, NUP107 NTD, ... | | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | | 登録日 | 2021-12-22 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (37 Å) | | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore.
Science, 376, 2022
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7TBK
 | | Composite structure of the dilated human nuclear pore complex (NPC) symmetric core generated with a 37A in situ cryo-ET map of CD4+ T cell NPC | | 分子名称: | NUP107 CTD, NUP107 NTD, NUP133, ... | | 著者 | Petrovic, S, Samanta, D, Perriches, T, Bley, C.J, Thierbach, K, Brown, B, Nie, S, Mobbs, G.W, Stevens, T.A, Liu, X, Tomaleri, G.P, Schaus, L, Hoelz, A. | | 登録日 | 2021-12-22 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-06-22 | | 実験手法 | ELECTRON MICROSCOPY (37 Å) | | 主引用文献 | Architecture of the linker-scaffold in the nuclear pore.
Science, 376, 2022
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7OVR
 | | Mature HIV-1 matrix structure | | 分子名称: | HIV-1 matrix, MYRISTIC ACID, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | | 著者 | Qu, K, Ke, Z.L, Zila, V, Anders-Oesswein, M, Glass, B, Muecksch, F, Mueller, R, Schultz, C, Mueller, B, Kraeusslich, H.G, Briggs, J.A.G. | | 登録日 | 2021-06-15 | | 公開日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (7 Å) | | 主引用文献 | Maturation of the matrix and viral membrane of HIV-1.
Science, 373, 2021
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7OVQ
 | | Immature HIV-1 matrix structure | | 分子名称: | Gag polyprotein, MYRISTIC ACID | | 著者 | Qu, K, Ke, Z.L, Zila, V, Anders-Oesswein, M, Glass, B, Muecksch, F, Mueller, R, Schultz, C, Mueller, B, Kraeusslich, H.G, Briggs, J.A.G. | | 登録日 | 2021-06-15 | | 公開日 | 2021-08-18 | | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | | 主引用文献 | Maturation of the matrix and viral membrane of HIV-1.
Science, 373, 2021
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4USN
 | | The structure of the immature HIV-1 capsid in intact virus particles at sub-nm resolution | | 分子名称: | P24 | | 著者 | Schur, F.K.M, Hagen, W.J.H, Rumlova, M, Ruml, T, Mueller, B, Kraeusslich, H.-G, Briggs, J.A.G. | | 登録日 | 2014-07-11 | | 公開日 | 2014-11-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | | 主引用文献 | Structure of the Immature HIV-1 Capsid in Intact Virus Particles at 8.8 A Resolution.
Nature, 517, 2015
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4U7Q
 | | Structure of wild-type HIV protease in complex with photosensitive inhibitor PDI-6 | | 分子名称: | N~2~-({[7-(diethylamino)-2-oxo-2H-chromen-4-yl]methoxy}carbonyl)-N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-L-valinamide, V-1 protease | | 著者 | Pachl, P, Rezacova, P, Schimer, J. | | 登録日 | 2014-07-31 | | 公開日 | 2015-03-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor.
Nat Commun, 6, 2015
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4U7V
 | | Structure of wild-type HIV protease in complex with degraded photosensitive inhibitor | | 分子名称: | BETA-MERCAPTOETHANOL, N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-L-valinamide, V-1 protease | | 著者 | Pachl, P, Rezacova, P, Schimer, J. | | 登録日 | 2014-07-31 | | 公開日 | 2015-03-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Triggering HIV polyprotein processing by light using rapid photodegradation of a tight-binding protease inhibitor.
Nat Commun, 6, 2015
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1N64
 | | Crystal structure analysis of the immunodominant antigenic site on Hepatitis C virus protein bound to mAb 19D9D6 | | 分子名称: | Fab 19D9D6 heavy chain, Fab 19D9D6 light chain, Genome polyprotein Capsid protein C | | 著者 | Menez, R, Bossus, M, Muller, B, Sibai, G, Dalbon, P, Ducancel, F, Jolivet-Reynaud, C, Stura, E. | | 登録日 | 2002-11-08 | | 公開日 | 2003-02-25 | | 最終更新日 | 2013-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.34 Å) | | 主引用文献 | Crystal structure of a hydrophobic immunodominant
antigenic site on hepatitis C virus core protein
complexed to monoclonal antibody 19D9D6.
J.Immunol., 170, 2003
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1NLB
 | | crystal structure of anti-HCV monoclonal antibody 19D9D6 | | 分子名称: | antibody 19D9D6 heavy chain, antibody 19D9D6 light chain | | 著者 | Menez, R, Bossus, M, Muller, B, Sibai, G, Dalbon, P, Ducancel, F, Jolivet-Reynaud, C, Stura, E. | | 登録日 | 2003-01-07 | | 公開日 | 2003-02-25 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of a hydrophobic immunodominant
antigenic site on hepatitis C virus core protein
complexed to monoclonal antibody 19D9D6.
J.Immunol., 170, 2003
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3WQS
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8FG0
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4KP7
 | | Structure of Plasmodium IspC in complex with a beta-thia-isostere derivative of Fosmidomycin | | 分子名称: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplast, MANGANESE (III) ION, ... | | 著者 | Kunfermann, A, Bacher, A, Groll, M. | | 登録日 | 2013-05-13 | | 公開日 | 2013-10-02 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | IspC as Target for Antiinfective Drug Discovery: Synthesis, Enantiomeric Separation, and Structural Biology of Fosmidomycin Thia Isosters.
J.Med.Chem., 56, 2013
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3WQR
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3WQQ
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6AZM
 | | Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer | | 分子名称: | 580 germline antibody, heavy chain, light chain, ... | | 著者 | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | 登録日 | 2017-09-11 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
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6B0S
 | | Crystal structure of circumsporozoite protein aTSR domain in complex with 1710 antibody | | 分子名称: | 1710 antibody, heavy chain, light chain, ... | | 著者 | Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | 登録日 | 2017-09-15 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
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6AZX
 | | Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody | | 分子名称: | 663 antibody, heavy chain, light chain | | 著者 | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | 登録日 | 2017-09-13 | | 公開日 | 2017-12-13 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
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6B0W
 | | Crystal structure of the anti-circumsporozoite protein 1710 antibody | | 分子名称: | 1710 antibody, heavy chain, light chain, ... | | 著者 | Scally, S.W, Murugan, R, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | 登録日 | 2017-09-15 | | 公開日 | 2017-11-08 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection.
J. Exp. Med., 215, 2018
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6D0X
 | | Crystal structure of chimeric H.2140 / K.1210 Fab in complex with circumsporozoite protein NANP3 | | 分子名称: | 1210 Antibody, light chain, 2140 Antibody, ... | | 著者 | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | | 登録日 | 2018-04-11 | | 公開日 | 2018-06-13 | | 最終更新日 | 2018-07-04 | | 実験手法 | X-RAY DIFFRACTION (1.849 Å) | | 主引用文献 | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.
Science, 360, 2018
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6D01
 | | Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5 | | 分子名称: | 1,2-ETHANEDIOL, 1210 Antibody, Light chain, ... | | 著者 | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | | 登録日 | 2018-04-09 | | 公開日 | 2018-06-13 | | 最終更新日 | 2018-07-04 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.
Science, 360, 2018
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6D11
 | | Crystal structure of 1450 Fab in complex with circumsporozoite protein NANP5 | | 分子名称: | 1450 Antibody, Heavy chain, Light chain, ... | | 著者 | Scally, S.W, Bosch, A, Imkeller, K, Wardemann, H, Julien, J.P. | | 登録日 | 2018-04-11 | | 公開日 | 2018-06-13 | | 最終更新日 | 2018-07-04 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope.
Science, 360, 2018
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5BK5
 | | Crystal structure of the anti-circumsporozoite protein 663 germline antibody | | 分子名称: | 663 germline antibody, heavy chain, light chain, ... | | 著者 | Scally, S.W, Bosch, A, Triller, G, Wardemann, H, Julien, J.P. | | 登録日 | 2017-09-12 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Immunity, 47, 2017
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