6AZX

Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody

Summary for 6AZX

Entry DOI	10.2210/pdb6azx/pdb
Related	5BK0 5BK3 5BK5 6AZM
Descriptor	663 antibody, heavy chain, 663 antibody, light chain (3 entities in total)
Functional Keywords	malaria, circumsporozoite protein, fab, immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	95759.21
Authors	Scally, S.W.,Bosch, A.,Triller, G.,Wardemann, H.,Julien, J.P. (deposition date: 2017-09-13, release date: 2017-12-13, Last modification date: 2023-10-04)
Primary citation	Triller, G.,Scally, S.W.,Costa, G.,Pissarev, M.,Kreschel, C.,Bosch, A.,Marois, E.,Sack, B.K.,Murugan, R.,Salman, A.M.,Janse, C.J.,Khan, S.M.,Kappe, S.H.I.,Adegnika, A.A.,Mordmuller, B.,Levashina, E.A.,Julien, J.P.,Wardemann, H. Natural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies. Immunity, 47:1197-1209.e10, 2017 Cited by PubMed: 29195810 DOI: 10.1016/j.immuni.2017.11.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation