8FG0

Crystal structure of the 3764 Fab in complex with the C-terminal PfCSP linker, PfCSP281-294.

Summary for 8FG0

Entry DOI	10.2210/pdb8fg0/pdb
Descriptor	3764 Fab Heavy chain, 3764 Fab Light chain, Circumsporozoite protein, ... (4 entities in total)
Functional Keywords	malaria, antibody, immune system
Biological source	Homo sapiens More
Total number of polymer chains	6
Total formula weight	99214.54
Authors	Burn Aschner, C.,Julien, J.P. (deposition date: 2022-12-11, release date: 2023-05-10, Last modification date: 2023-06-14)
Primary citation	Oludada, O.E.,Costa, G.,Burn Aschner, C.,Obraztsova, A.S.,Prieto, K.,Canetta, C.,Hoffman, S.L.,Kremsner, P.G.,Mordmuller, B.,Murugan, R.,Julien, J.P.,Levashina, E.A.,Wardemann, H. Molecular and functional properties of human Plasmodium falciparum CSP C-terminus antibodies. Embo Mol Med, 15:e17454-e17454, 2023 Cited by PubMed: 37082831 DOI: 10.15252/emmm.202317454 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.36 Å)

Structure validation