2BEX
| Crystal structure of Placental Ribonuclease Inhibitor in complex with Human Eosinophil Derived Neurotoxin at 2A resolution | 分子名称: | ALPHA-KETOMALONIC ACID, GLYCEROL, NONSECRETORY RIBONUCLEASE, ... | 著者 | Iyer, S, Holloway, D.E, Kumar, K, Shapiro, R, Acharya, K.R. | 登録日 | 2004-12-01 | 公開日 | 2005-03-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Molecular Recognition of Human Eosinophil-Derived Neurotoxin (Rnase 2) by Placental Ribonuclease Inhibitor J.Mol.Biol., 347, 2005
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1FZV
| THE CRYSTAL STRUCTURE OF HUMAN PLACENTA GROWTH FACTOR-1 (PLGF-1), AN ANGIOGENIC PROTEIN AT 2.0A RESOLUTION | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, PLACENTA GROWTH FACTOR | 著者 | Iyer, S, Leonidas, D.D, Swaminathan, G.J, Maglione, D, Battisti, M, Tucci, M, Persico, M.G, Acharya, K.R. | 登録日 | 2000-10-04 | 公開日 | 2001-05-09 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The crystal structure of human placenta growth factor-1 (PlGF-1), an angiogenic protein, at 2.0 A resolution. J.Biol.Chem., 276, 2001
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2J0T
| Crystal Structure of the Catalytic Domain of MMP-1 in Complex with the Inhibitory Domain of TIMP-1 | 分子名称: | CALCIUM ION, INTERSTITIAL COLLAGENASE, METALLOPROTEINASE INHIBITOR 1, ... | 著者 | Iyer, S, Wei, S, Brew, K, Acharya, K.R. | 登録日 | 2006-08-04 | 公開日 | 2006-10-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Matrix Metalloproteinase-1 in Complex with the Inhibitory Domain of Tissue Inhibitor of Metalloproteinase-1. J.Biol.Chem., 282, 2007
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2CLT
| Crystal structure of the active form (full-length) of human fibroblast collagenase. | 分子名称: | CALCIUM ION, INTERSTITIAL COLLAGENASE, ZINC ION | 著者 | Iyer, S, Visse, R, Nagase, H, Acharya, K.R. | 登録日 | 2006-04-29 | 公開日 | 2006-08-09 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal Structure of an Active Form of Human Mmp-1. J.Mol.Biol., 362, 2006
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2C7W
| Crystal Structure of human vascular endothelial growth factor-B: Identification of amino acids important for angiogeninc activity | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, VASCULAR ENDOTHELIAL GROWTH FACTOR B PRECURSOR | 著者 | Iyer, S, Scotney, P.D, Nash, A.D, Acharya, K.R. | 登録日 | 2005-11-29 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding J.Mol.Biol., 359, 2006
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4S2R
| Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site | 分子名称: | Protein APP-1, ZINC ION | 著者 | Iyer, S, La-Borde, P, Payne, K.A.P, Parsons, M.R, Turner, A.J, Isaac, R.E, Acharya, K.R. | 登録日 | 2015-01-22 | 公開日 | 2015-04-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site. FEBS Open Bio, 5, 2015
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4S2T
| Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: a cytosolic enzyme with a di-nuclear active site | 分子名称: | Protein APP-1, SULFATE ION, ZINC ION, ... | 著者 | Iyer, S, La-Borde, P, Payne, K.A.P, Parsons, M.R, Turner, A.J, Isaac, R.E, Acharya, K.R. | 登録日 | 2015-01-22 | 公開日 | 2015-04-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site. FEBS Open Bio, 5, 2015
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3ZBW
| Crystal Structure of murine Angiogenin-3 | 分子名称: | ACETIC ACID, ANGIOGENIN-3, SULFATE ION, ... | 著者 | Iyer, S, Holloway, D.E, Acharya, K.R. | 登録日 | 2012-11-13 | 公開日 | 2012-12-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.801 Å) | 主引用文献 | Crystal Structures of Murine Angiogenin-2 and -3 - Probing 'Structure - Function' Relationships Amongst Angiogenin Homologues. FEBS J., 280, 2013
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3ZBV
| Crystal Structure of murine Angiogenin-2 | 分子名称: | ANGIOGENIN-2, GLYCEROL, SULFATE ION, ... | 著者 | Iyer, S, Holloway, D.E, Acharya, K.R. | 登録日 | 2012-11-13 | 公開日 | 2012-12-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal Structures of Murine Angiogenin-2 and -3 - Probing 'Structure - Function' Relationships Amongst Angiogenin Homologues. FEBS J., 280, 2013
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2XAC
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8TXO
| E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D. | 登録日 | 2023-08-23 | 公開日 | 2024-01-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Overcoming resolution attenuation during tilted cryo-EM data collection. Nat Commun, 15, 2024
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2M9U
| Solution NMR structure of the C-terminal domain (CTD) of Moloney murine leukemia virus integrase, Northeast Structural Genomics Target OR41A | 分子名称: | Integrase p46 | 著者 | Aiyer, S, Rossi, P, Schneider, W.M, Chander, A, Roth, M.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2013-06-19 | 公開日 | 2013-12-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Altering murine leukemia virus integration through disruption of the integrase and BET protein family interaction. Nucleic Acids Res., 42, 2014
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7JYZ
| Solution NMR structure and dynamics of human Brd3 ET in complex with MLV IN CTD | 分子名称: | Bromodomain-containing protein 3, Integrase | 著者 | Aiyer, S, Liu, G, Swapna, G.V.T, Hao, J, Ma, L.C, Roth, M.J, Montelione, G.T. | 登録日 | 2020-09-01 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins. Structure, 29, 2021
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7JQ8
| Solution NMR structure of human Brd3 ET domain | 分子名称: | Bromodomain-containing protein 3, Integrase peptide | 著者 | Aiyer, S, Swapna, G.V.T, Roth, J.M, Montelione, G.T. | 登録日 | 2020-08-10 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins. Structure, 29, 2021
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7JYN
| Solution NMR structure of human Brd3 ET complexed with NSD3(148-184) peptide | 分子名称: | Bromodomain-containing protein 3, Histone-lysine N-methyltransferase NSD3 | 著者 | Aiyer, S, Swapna, G.V.T, Roth, M.J, Montelione, G.T. | 登録日 | 2020-08-31 | 公開日 | 2021-06-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins. Structure, 29, 2021
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7JMY
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6ULH
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6UMS
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6P5H
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6P5B
| Crystal Structure of MavC in Complex with Ub-UbE2N | 分子名称: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | 著者 | Puvar, K, Iyer, S, Negron Teron, K.I, Das, C. | 登録日 | 2019-05-30 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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2WK6
| Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil | 分子名称: | 5-IODOURACIL, THYMIDINE PHOSPHORYLASE | 著者 | Mitsiki, E, Papageorgiou, A.C, Iyer, S, Thiyagarajan, N, Prior, S.H, Sleep, D, Finnis, C, Acharya, K.R. | 登録日 | 2009-06-05 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil. Biochem.Biophys.Res.Commun., 386, 2009
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2WK5
| Structural features of native human thymidine phosphorylase and in complex with 5-iodouracil | 分子名称: | GLYCEROL, THYMIDINE PHOSPHORYLASE | 著者 | Mitsiki, E, Papageorgiou, A.C, Iyer, S, Thiyagarajan, N, Prior, S.H, Sleep, D, Finnis, C, Acharya, K.R. | 登録日 | 2009-06-05 | 公開日 | 2009-07-07 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structures of Native Human Thymidine Phosphorylase and in Complex with 5-Iodouracil. Biochem.Biophys.Res.Commun., 386, 2009
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2VWE
| Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralizing Antibody Fab Fragment | 分子名称: | ANTI-VEGF-B MONOCLONAL ANTIBODY, VASCULAR ENDOTHELIAL GROWTH FACTOR B | 著者 | Leonard, P, Scotney, P.D, Jabeen, T, Iyer, S, Fabri, L.J, Nash, A.D, Acharya, K.R. | 登録日 | 2008-06-23 | 公開日 | 2008-11-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure of Vascular Endothelial Growth Factor-B in Complex with a Neutralising Antibody Fab Fragment. J.Mol.Biol., 384, 2008
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6UMP
| Crystal structure of MavC in complex with substrate mimic in P65 space group | 分子名称: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | 著者 | Puvar, K, Iyer, S, Luo, Z.Q, Das, C. | 登録日 | 2019-10-10 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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6E9D
| Sub-2 Angstrom Ewald Curvature-Corrected Single-Particle Cryo-EM Reconstruction of AAV-2 L336C | 分子名称: | Capsid protein VP1 | 著者 | Tan, Y.Z, Aiyer, S, Mietzsch, M, Hull, J.A, McKenna, R, Baker, T.S, Agbandje-McKenna, M, Lyumkis, D. | 登録日 | 2018-07-31 | 公開日 | 2018-08-15 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (1.86 Å) | 主引用文献 | Sub-2 angstrom Ewald curvature corrected structure of an AAV2 capsid variant. Nat Commun, 9, 2018
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