2BEX

Crystal structure of Placental Ribonuclease Inhibitor in complex with Human Eosinophil Derived Neurotoxin at 2A resolution

Summary for 2BEX

Entry DOI	10.2210/pdb2bex/pdb
Related	1A4Y 1GQV 1HI2 1HI3 1HI4 1HI5 1K2A
Descriptor	RIBONUCLEASE INHIBITOR, NONSECRETORY RIBONUCLEASE, GLYCEROL, ... (5 entities in total)
Functional Keywords	hydrolase/inhibitor, complex (inhibitor-nuclease), ribonuclease inhibitor, eosinophil derived neurotoxin, rnase 2, luecine-rich repeats, protein-protein interaction, molecular recognition, hydrolase-inhibitor complex
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Cytoplasm: P13489 Lysosome (Probable): P10153
Total number of polymer chains	4
Total formula weight	131207.95
Authors	Iyer, S.,Holloway, D.E.,Kumar, K.,Shapiro, R.,Acharya, K.R. (deposition date: 2004-12-01, release date: 2005-03-17, Last modification date: 2023-12-13)
Primary citation	Iyer, S.,Holloway, D.E.,Kumar, K.,Shapiro, R.,Acharya, K.R. Molecular Recognition of Human Eosinophil-Derived Neurotoxin (Rnase 2) by Placental Ribonuclease Inhibitor J.Mol.Biol., 347:637-, 2005 Cited by PubMed: 15755456 DOI: 10.1016/J.JMB.2005.01.035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation