6E9D

Sub-2 Angstrom Ewald Curvature-Corrected Single-Particle Cryo-EM Reconstruction of AAV-2 L336C

This is a non-PDB format compatible entry.

Summary for 6E9D

• Entry DOI: 10.2210/pdb6e9d/pdb
• EMDB information: 9012
• Descriptor: Capsid protein VP1 (2 entities in total)
• Functional Keywords: aav-2 l336c, gene therapy, ewald sphere curvature correction, per particle ctf, virus like particle
• Biological source: Adeno-associated virus 2 Srivastava/1982 (AAV-2)
• Total number of polymer chains: 60
• Total formula weight: 4921280.16

Authors

Tan, Y.Z.,Aiyer, S.,Mietzsch, M.,Hull, J.A.,McKenna, R.,Baker, T.S.,Agbandje-McKenna, M.,Lyumkis, D. (deposition date: 2018-07-31, release date: 2018-08-15, Last modification date: 2024-03-13)

• Primary citation: Tan, Y.Z.,Aiyer, S.,Mietzsch, M.,Hull, J.A.,McKenna, R.,Grieger, J.,Samulski, R.J.,Baker, T.S.,Agbandje-McKenna, M.,Lyumkis, D.; Sub-2 angstrom Ewald curvature corrected structure of an AAV2 capsid variant.; Nat Commun, 9:3628-3628, 2018; PubMed: 30194371; DOI: 10.1038/s41467-018-06076-6

Experimental method

ELECTRON MICROSCOPY (1.86 Å)