2BBM
 
 | | SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR | | 分子名称: | CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE | | 著者 | Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. | | 登録日 | 1992-07-16 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a calmodulin-target peptide complex by multidimensional NMR.
Science, 256, 1992
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2BBN
 | | SOLUTION STRUCTURE OF A CALMODULIN-TARGET PEPTIDE COMPLEX BY MULTIDIMENSIONAL NMR | | 分子名称: | CALCIUM ION, CALMODULIN, MYOSIN LIGHT CHAIN KINASE | | 著者 | Clore, G.M, Bax, A, Ikura, M, Gronenborn, A.M. | | 登録日 | 1992-07-16 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a calmodulin-target peptide complex by multidimensional NMR.
Science, 256, 1992
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3UJ4
 | | Crystal structure of the apo-inositol 1,4,5-trisphosphate receptor | | 分子名称: | Inositol 1,4,5-trisphosphate receptor type 1, SULFATE ION | | 著者 | Ikura, M, Seo, M.D, Ishiyama, N, Stathopulos, P. | | 登録日 | 2011-11-07 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
Nature, 483, 2012
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3UJ0
 | | Crystal structure of the inositol 1,4,5-trisphosphate receptor with ligand bound form. | | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1 | | 著者 | Ikura, M, Seo, M.D, Ishiyama, N, Stathopulos, P. | | 登録日 | 2011-11-07 | | 公開日 | 2012-02-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
Nature, 483, 2012
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5WI4
 | | CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2 | | 分子名称: | Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION | | 著者 | Balan, M, Ishiyama, N, Marshall, C.B, Ikura, M. | | 登録日 | 2017-07-18 | | 公開日 | 2017-11-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
Sci Signal, 10, 2017
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3JRR
 | | Crystal structure of the ligand binding suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor | | 分子名称: | Inositol 1,4,5-trisphosphate receptor type 3 | | 著者 | Chan, J, Ishiyama, N, Ikura, M. | | 登録日 | 2009-09-08 | | 公開日 | 2010-09-15 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | A 1.9 angstrom crystal structure of the suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor
To be Published
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8VM2
 | | Crystal Structure of NRAS Q61K bound to GTP | | 分子名称: | GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Gebregiworgis, T, Chan, J.Y.L, Kuntz, D.A, Prive, G.G, Marshall, C.B, Ikura, M. | | 登録日 | 2024-01-12 | | 公開日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II.
Eur J Cell Biol, 103, 2024
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6OS4
 | | Calmodulin in complex with farnesyl cysteine methyl ester | | 分子名称: | CALCIUM ION, Calmodulin-1, s-farnesyl-l-cysteine methyl ester | | 著者 | Grant, B.M.M, Enomoto, M, Lee, K.Y, Back, S.I, Gebregiworgis, T, Ishiyama, N, Ikura, M, Marshall, C. | | 登録日 | 2019-05-01 | | 公開日 | 2020-04-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety.
Sci.Signal., 13, 2020
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4B0A
 | | The high-resolution structure of yTBP-yTAF1 identifies conserved and competing interaction surfaces in transcriptional activation | | 分子名称: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Anandapadamanaban, M, Andresen, C, Siponen, M, Kokubo, T, Ikura, M, Moche, M, Sunnerhagen, M. | | 登録日 | 2012-06-29 | | 公開日 | 2013-07-03 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | High-Resolution Structure of TBP with Taf1 Reveals Anchoring Patterns in Transcriptional Regulation
Nat.Struct.Mol.Biol., 20, 2013
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6W4F
 | | NMR-driven structure of KRAS4B-GDP homodimer on a lipid bilayer nanodisc | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Lee, K, Fang, Z, Enomoto, M, Gasmi-Seabrook, G.M, Zheng, L, Marshall, C.B, Ikura, M. | | 登録日 | 2020-03-10 | | 公開日 | 2020-04-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6W4E
 | | NMR-driven structure of KRAS4B-GTP homodimer on a lipid bilayer nanodisc | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, ... | | 著者 | Lee, K, Fang, Z, Enomoto, M, Gasmi-Seabrook, G.M, Zheng, L, Marshall, C.B, Ikura, M. | | 登録日 | 2020-03-10 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement.
Angew.Chem.Int.Ed.Engl., 59, 2020
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3HSM
 | | Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1 | | 分子名称: | Ryanodine receptor 1 | | 著者 | Amador, F.J, Liu, S, Ishiyama, N, Plevin, M.J, Wilson, A, MacLennan, D.H, Ikura, M. | | 登録日 | 2009-06-10 | | 公開日 | 2009-07-28 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation "hot spot" loop
Proc.Natl.Acad.Sci.USA, 106, 2009
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1IQ5
 | | Calmodulin/nematode CA2+/Calmodulin dependent kinase kinase fragment | | 分子名称: | CA2+/CALMODULIN DEPENDENT KINASE KINASE, CALCIUM ION, CALMODULIN | | 著者 | Kurokawa, H, Osawa, M, Kurihara, H, Katayama, N, Tokumitsu, H, Swindells, M.B, Kainosho, M, Ikura, M. | | 登録日 | 2001-06-14 | | 公開日 | 2001-09-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Target-induced conformational adaptation of calmodulin revealed by the crystal structure of a complex with nematode Ca(2+)/calmodulin-dependent kinase kinase peptide
J.Mol.Biol., 312, 2001
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1PRS
 | | NMR-DERIVED THREE-DIMENSIONAL SOLUTION STRUCTURE OF PROTEIN S COMPLEXED WITH CALCIUM | | 分子名称: | CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S | | 著者 | Bagby, S, Harvey, T.S, Eagle, S.G, Inouye, S, Ikura, M. | | 登録日 | 1994-03-25 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR-derived three-dimensional solution structure of protein S complexed with calcium.
Structure, 2, 1994
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1PRR
 | | NMR-DERIVED THREE-DIMENSIONAL SOLUTION STRUCTURE OF PROTEIN S COMPLEXED WITH CALCIUM | | 分子名称: | CALCIUM ION, DEVELOPMENT-SPECIFIC PROTEIN S | | 著者 | Bagby, S, Harvey, T.S, Eagle, S.G, Inouye, S, Ikura, M. | | 登録日 | 1994-03-25 | | 公開日 | 1994-08-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR-derived three-dimensional solution structure of protein S complexed with calcium.
Structure, 2, 1994
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7SCX
 | | KRAS full-length G12V in complex with RGL1 Ras association domain | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | | 著者 | Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B. | | 登録日 | 2021-09-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J.Mol.Biol., 434, 2022
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7SCW
 | | KRAS full length wild-type in complex with RGL1 Ras association domain | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Isoform 2B of GTPase KRas, MAGNESIUM ION, ... | | 著者 | Eves, B.J, Kuntz, D.A, Ikura, M, Marshall, C.B. | | 登録日 | 2021-09-29 | | 公開日 | 2022-05-18 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.
J.Mol.Biol., 434, 2022
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1SUH
 | | AMINO-TERMINAL DOMAIN OF EPITHELIAL CADHERIN IN THE CALCIUM BOUND STATE, NMR, 20 STRUCTURES | | 分子名称: | EPITHELIAL CADHERIN | | 著者 | Overduin, M, Tong, K.I, Kay, C.M, Ikura, M. | | 登録日 | 1996-01-30 | | 公開日 | 1996-07-11 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | 1H, 15N and 13C resonance assignments and monomeric structure of the amino-terminal extracellular domain of epithelial cadherin.
J.Biomol.NMR, 7, 1996
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1BXD
 | | NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ | | 分子名称: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (OSMOLARITY SENSOR PROTEIN (ENVZ)) | | 著者 | Tanaka, T, Saha, S.K, Tomomori, C, Ishima, R, Liu, D, Tong, K.I, Park, H, Dutta, R, Qin, L, Swindells, M.B, Yamazaki, T, Ono, A.M, Kainosho, M, Inouye, M, Ikura, M. | | 登録日 | 1998-10-02 | | 公開日 | 1999-10-02 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ.
Nature, 396, 1998
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3L6Y
 | | Crystal structure of p120 catenin in complex with E-cadherin | | 分子名称: | Catenin delta-1, E-cadherin | | 著者 | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | | 登録日 | 2009-12-27 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
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3L6X
 | | Crystal structure of p120 catenin in complex with E-cadherin | | 分子名称: | Catenin delta-1, E-cadherin, SULFATE ION | | 著者 | Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M. | | 登録日 | 2009-12-27 | | 公開日 | 2010-04-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
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6PW7
 | | X-ray crystal structure of C. elegans STIM EF-SAM domain | | 分子名称: | CALCIUM ION, Stromal interaction molecule 1 | | 著者 | Enomoto, M, Nishikawa, T, Back, S.I, Ishiyama, N, Zheng, L, Stathopulos, P.B, Ikura, M. | | 登録日 | 2019-07-22 | | 公開日 | 2019-11-13 | | 最終更新日 | 2020-02-12 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain.
J.Mol.Biol., 432, 2020
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7RSE
 | | NMR-driven structure of the KRAS4B-G12D "alpha-beta" dimer on a lipid bilayer nanodisc | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Lee, K, Enomoto, M, Gebregiworgis, T, Gasmi-Seabrook, G.M, Ikura, M, Marshall, C.B. | | 登録日 | 2021-08-11 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization.
Chem Sci, 12, 2021
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7RSC
 | | NMR-driven structure of the KRAS4B-G12D "alpha-alpha" dimer on a lipid bilayer nanodisc | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Apolipoprotein A-I, GTPase KRas, ... | | 著者 | Lee, K, Enomoto, M, Gebregiworgis, T, Gasmi-Seabrook, G.M, Ikura, M, Marshall, C.B. | | 登録日 | 2021-08-11 | | 公開日 | 2021-09-22 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Oncogenic KRAS G12D mutation promotes dimerization through a second, phosphatidylserine-dependent interface: a model for KRAS oligomerization.
Chem Sci, 12, 2021
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1TFB
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