7SCX
KRAS full-length G12V in complex with RGL1 Ras association domain
Summary for 7SCX
Entry DOI | 10.2210/pdb7scx/pdb |
Descriptor | Isoform 2B of GTPase KRas, Ral guanine nucleotide dissociation stimulator-like 1, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | gtpase, ralgef, complex, domain-swap, oncoprotein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 32839.17 |
Authors | Eves, B.J.,Kuntz, D.A.,Ikura, M.,Marshall, C.B. (deposition date: 2021-09-29, release date: 2022-05-18, Last modification date: 2023-10-25) |
Primary citation | Eves, B.J.,Gebregiworgis, T.,Gasmi-Seabrook, G.M.C.,Kuntz, D.A.,Prive, G.G.,Marshall, C.B.,Ikura, M. Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant. J.Mol.Biol., 434:167527-167527, 2022 Cited by PubMed: 35257782DOI: 10.1016/j.jmb.2022.167527 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.96 Å) |
Structure validation
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