7SCX

KRAS full-length G12V in complex with RGL1 Ras association domain

Summary for 7SCX

• Entry DOI: 10.2210/pdb7scx/pdb
• Descriptor: Isoform 2B of GTPase KRas, Ral guanine nucleotide dissociation stimulator-like 1, MAGNESIUM ION, ... (6 entities in total)
• Functional Keywords: gtpase, ralgef, complex, domain-swap, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 32839.17

Authors

Eves, B.J.,Kuntz, D.A.,Ikura, M.,Marshall, C.B. (deposition date: 2021-09-29, release date: 2022-05-18, Last modification date: 2023-10-25)

• Primary citation: Eves, B.J.,Gebregiworgis, T.,Gasmi-Seabrook, G.M.C.,Kuntz, D.A.,Prive, G.G.,Marshall, C.B.,Ikura, M.; Structures of RGL1 RAS-Association Domain in Complex with KRAS and the Oncogenic G12V Mutant.; J.Mol.Biol., 434:167527-167527, 2022; PubMed: 35257782; DOI: 10.1016/j.jmb.2022.167527

Experimental method

X-RAY DIFFRACTION (1.96 Å)