3HSM

Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1

Summary for 3HSM

Entry DOI	10.2210/pdb3hsm/pdb
Descriptor	Ryanodine receptor 1 (2 entities in total)
Functional Keywords	beta-trefoil, calcium, calcium channel, calcium transport, glycoprotein, ion transport, ionic channel, membrane, phosphoprotein, receptor, s-nitrosylation, transmembrane, transport, signaling protein
Biological source	Oryctolagus cuniculus (rabbit)
Cellular location	Sarcoplasmic reticulum membrane ; Multi-pass membrane protein : P11716
Total number of polymer chains	2
Total formula weight	46550.46
Authors	Amador, F.J.,Liu, S.,Ishiyama, N.,Plevin, M.J.,Wilson, A.,MacLennan, D.H.,Ikura, M. (deposition date: 2009-06-10, release date: 2009-07-28, Last modification date: 2023-09-06)
Primary citation	Amador, F.J.,Liu, S.,Ishiyama, N.,Plevin, M.J.,Wilson, A.,MacLennan, D.H.,Ikura, M. Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation "hot spot" loop Proc.Natl.Acad.Sci.USA, 106:11040-11044, 2009 Cited by PubMed: 19541610 DOI: 10.1073/pnas.0905186106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation