8VM2

Crystal Structure of NRAS Q61K bound to GTP

Summary for 8VM2

Entry DOI	10.2210/pdb8vm2/pdb
Descriptor	GTPase NRas, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywords	nras, oncogenic mutation, ras superfamily small gtpases, hydrolase, hydrolase-oncoprotein complex, hydrolase/oncoprotein
Biological source	Homo sapiens (human)
Total number of polymer chains	3
Total formula weight	68042.84
Authors	Gebregiworgis, T.,Chan, J.Y.L.,Kuntz, D.A.,Prive, G.G.,Marshall, C.B.,Ikura, M. (deposition date: 2024-01-12, release date: 2024-05-01)
Primary citation	Gebregiworgis, T.,Chan, J.Y.,Kuntz, D.A.,Prive, G.G.,Marshall, C.B.,Ikura, M. Crystal structure of NRAS Q61K with a ligand-induced pocket near switch II. Eur J Cell Biol, 103:151414-151414, 2024 Cited by PubMed: 38640594 DOI: 10.1016/j.ejcb.2024.151414 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.74 Å)

Structure validation