6W4E
NMR-driven structure of KRAS4B-GTP homodimer on a lipid bilayer nanodisc
Summary for 6W4E
| Entry DOI | 10.2210/pdb6w4e/pdb |
| NMR Information | BMRB: 30734 |
| Descriptor | Apolipoprotein A-I, GTPase KRas, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total) |
| Functional Keywords | gtpase, nanodisc, oncoprotein |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 152840.20 |
| Authors | Lee, K.,Fang, Z.,Enomoto, M.,Gasmi-Seabrook, G.M.,Zheng, L.,Marshall, C.B.,Ikura, M. (deposition date: 2020-03-10, release date: 2020-04-15, Last modification date: 2020-07-08) |
| Primary citation | Lee, K.Y.,Fang, Z.,Enomoto, M.,Gasmi-Seabrook, G.,Zheng, L.,Koide, S.,Ikura, M.,Marshall, C.B. Two Distinct Structures of Membrane-Associated Homodimers of GTP- and GDP-Bound KRAS4B Revealed by Paramagnetic Relaxation Enhancement. Angew.Chem.Int.Ed.Engl., 59:11037-11045, 2020 Cited by PubMed: 32227412DOI: 10.1002/anie.202001758 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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