3UJ0
Crystal structure of the inositol 1,4,5-trisphosphate receptor with ligand bound form.
Summary for 3UJ0
Entry DOI | 10.2210/pdb3uj0/pdb |
Related | 3UJ4 |
Descriptor | Inositol 1,4,5-trisphosphate receptor type 1, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE (3 entities in total) |
Functional Keywords | inositol 1, 4, 5-trisphosphate, ip3-bound form, suppressor domain, ip3-binding core domain, signaling protein |
Biological source | Rattus norvegicus (brown rat,rat,rats) |
Cellular location | Endoplasmic reticulum membrane; Multi-pass membrane protein: P29994 |
Total number of polymer chains | 2 |
Total formula weight | 136823.65 |
Authors | Ikura, M.,Seo, M.D.,Ishiyama, N.,Stathopulos, P. (deposition date: 2011-11-07, release date: 2012-02-15, Last modification date: 2024-02-28) |
Primary citation | Seo, M.D.,Velamakanni, S.,Ishiyama, N.,Stathopulos, P.B.,Rossi, A.M.,Khan, S.A.,Dale, P.,Li, C.,Ames, J.B.,Ikura, M.,Taylor, C.W. Structural and functional conservation of key domains in InsP3 and ryanodine receptors. Nature, 483:108-112, 2012 Cited by PubMed: 22286060DOI: 10.1038/nature10751 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
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