3UJ0

Crystal structure of the inositol 1,4,5-trisphosphate receptor with ligand bound form.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Inositol 1,4,5-trisphosphate receptor type 1	polymer	604	67991.7	2	UniProt (P29994) Pfam (PF08709) Pfam (PF02815) Pfam (PF01365) In PDB	Rattus norvegicus (brown rat rat rats)	IP-3-R, IP3R 1, InsP3R1, Type 1 inositol 1,4,5-trisphosphate receptor, Type 1 InsP3 receptor
2	A, B	D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE	non-polymer		420.1	2	Chemie (I3P)
3		water	water		18.0	9	Chemie (HOH)

Sequence modifications

A, B: 1 - 604 (UniProt: P29994)

PDB	External Database	Details
Ala 15	Cys 15	engineered mutation
Ala 37	Cys 37	engineered mutation
Ala 56	Cys 56	engineered mutation
Ala 61	Cys 61	engineered mutation
Ala 206	Cys 206	engineered mutation
Ala 214	Cys 214	engineered mutation
Ala 253	Cys 253	engineered mutation
Ala 292	Cys 292	engineered mutation
Ala 326	Cys 326	engineered mutation
Ala 394	Cys 394	engineered mutation
Ala 530	Cys 530	engineered mutation
Ala 553	Cys 553	engineered mutation
Ala 556	Cys 556	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	135983.5
Non-Polymers*	Number of molecules	2
	Total formula weight	840.2
All*	Total formula weight	136823.6

*Water molecules are not included.