8HCG
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![BU of 8hcg by Molmil](/molmil-images/mine/8hcg) | Crystal structure of mTREX1-dAMP complex | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | 登録日 | 2022-11-01 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.799 Å) | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCD
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![BU of 8hcd by Molmil](/molmil-images/mine/8hcd) | Crystal structure of mTREX1-DNA product complex (dNMP) | 分子名称: | 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, COBALT (II) ION, ... | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | 登録日 | 2022-11-01 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCE
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![BU of 8hce by Molmil](/molmil-images/mine/8hce) | Crystal structure of mTREX1-CMP complex | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AMMONIUM ION, CYTIDINE-5'-MONOPHOSPHATE, ... | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | 登録日 | 2022-11-01 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.501 Å) | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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8HCF
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![BU of 8hcf by Molmil](/molmil-images/mine/8hcf) | Crystal structure of mTREX1-UMP complex | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION, Three-prime repair exonuclease 1, ... | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | 登録日 | 2022-11-01 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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7V3A
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![BU of 7v3a by Molmil](/molmil-images/mine/7v3a) | Crystal structure of apo-NP exonuclease C409A | 分子名称: | MAGNESIUM ION, Nucleoprotein, ZINC ION | 著者 | Hsiao, Y.Y, Huang, K.W. | 登録日 | 2021-08-10 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V38
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![BU of 7v38 by Molmil](/molmil-images/mine/7v38) | Crystal structure of NP exonuclease-PCMPS complex | 分子名称: | Nucleoprotein, PARA-MERCURY-BENZENESULFONIC ACID, ZINC ION | 著者 | Hsiao, Y.Y, Huang, K.W. | 登録日 | 2021-08-10 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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8HCC
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![BU of 8hcc by Molmil](/molmil-images/mine/8hcc) | Crystal structure of mTREX1-RNA product complex (AMP) | 分子名称: | ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | 登録日 | 2022-11-01 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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7V3C
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![BU of 7v3c by Molmil](/molmil-images/mine/7v3c) | |
8HCH
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![BU of 8hch by Molmil](/molmil-images/mine/8hch) | Crystal structure of mTREX1-Uridine complex | 分子名称: | MAGNESIUM ION, Three-prime repair exonuclease 1, URIDINE | 著者 | Hsiao, Y.Y, Huang, K.W, Wu, C.Y. | 登録日 | 2022-11-01 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51, 2023
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7V39
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![BU of 7v39 by Molmil](/molmil-images/mine/7v39) | Crystal structure of NP exonuclease-PCMB complex | 分子名称: | 4-(HYDROXYMERCURY)BENZOIC ACID, Nucleoprotein, ZINC ION | 著者 | Hsiao, Y.Y, Huang, K.W. | 登録日 | 2021-08-10 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V37
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![BU of 7v37 by Molmil](/molmil-images/mine/7v37) | Crystal structure of apo-NP exonuclease | 分子名称: | Nucleoprotein, ZINC ION | 著者 | Hsiao, Y.Y, Huang, K.W. | 登録日 | 2021-08-10 | 公開日 | 2021-12-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.403 Å) | 主引用文献 | Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1, 2021
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7V3B
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![BU of 7v3b by Molmil](/molmil-images/mine/7v3b) | |
5YWT
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![BU of 5ywt by Molmil](/molmil-images/mine/5ywt) | |
5YWU
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![BU of 5ywu by Molmil](/molmil-images/mine/5ywu) | |
5YWS
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![BU of 5yws by Molmil](/molmil-images/mine/5yws) | |
5YWV
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![BU of 5ywv by Molmil](/molmil-images/mine/5ywv) | |
6KLA
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![BU of 6kla by Molmil](/molmil-images/mine/6kla) | Crystal structure of human c-KIT kinase domain in complex with compound 15a | 分子名称: | Mast/stem cell growth factor receptor Kit, N-[6-(4-ethylpiperazin-1-yl)-2-methyl-pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine | 著者 | Wu, T.S, Peng, Y.H, Hsueh, C.C, Wu, S.Y. | 登録日 | 2019-07-30 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.109 Å) | 主引用文献 | Identification of a Multitargeted Tyrosine Kinase Inhibitor for the Treatment of Gastrointestinal Stromal Tumors and Acute Myeloid Leukemia. J.Med.Chem., 62, 2019
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6A46
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![BU of 6a46 by Molmil](/molmil-images/mine/6a46) | |
6A4B
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![BU of 6a4b by Molmil](/molmil-images/mine/6a4b) | |
6A47
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![BU of 6a47 by Molmil](/molmil-images/mine/6a47) | Structure of TREX2 in complex with a Y structured dsDNA | 分子名称: | DNA (5'-D(P*CP*CP*AP*GP*GP*CP*CP*CP*TP*CP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3'), MAGNESIUM ION, SODIUM ION, ... | 著者 | Hsiao, Y.Y. | 登録日 | 2018-06-19 | 公開日 | 2018-11-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the duplex DNA processing of TREX2 Nucleic Acids Res., 46, 2018
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6A45
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![BU of 6a45 by Molmil](/molmil-images/mine/6a45) | Structure of mouse TREX2 | 分子名称: | PHOSPHATE ION, Three prime repair exonuclease 2 | 著者 | Hsiao, Y.Y. | 登録日 | 2018-06-19 | 公開日 | 2018-11-07 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Structural insights into the duplex DNA processing of TREX2 Nucleic Acids Res., 46, 2018
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