5YWT
Crystal structure of TREX1 in complex with a duplex DNA with 3' overhang
Summary for 5YWT
Entry DOI | 10.2210/pdb5ywt/pdb |
Descriptor | Three-prime repair exonuclease 1, DNA (5'-D(*GP*GP*CP*CP*CP*T)-3'), MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | trex1, exonuclease, deddh family, protein-dna complex, dna binding protein-dna complex, dna binding protein |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus: Q91XB0 |
Total number of polymer chains | 4 |
Total formula weight | 71555.24 |
Authors | Hsiao, Y.Y. (deposition date: 2017-11-30, release date: 2018-05-23, Last modification date: 2024-07-17) |
Primary citation | Huang, K.W.,Liu, T.C.,Liang, R.Y.,Chu, L.Y.,Cheng, H.L.,Chu, J.W.,Hsiao, Y.Y. Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1 PLoS Biol., 16:e2005653-e2005653, 2018 Cited by PubMed: 29734329DOI: 10.1371/journal.pbio.2005653 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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