5YWT
Crystal structure of TREX1 in complex with a duplex DNA with 3' overhang
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | ASP18 |
| A | LEU19 |
| A | GLU20 |
| A | ASP200 |
| A | MG304 |
| C | DT9 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue CO A 302 |
| Chain | Residue |
| A | ALA214 |
| A | HOH680 |
| A | HOH688 |
| A | LYS211 |
| A | PRO212 |
| A | GLN213 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue CO A 303 |
| Chain | Residue |
| A | GLN12 |
| A | HIS40 |
| A | ALA76 |
| A | PRO116 |
| A | HOH458 |
| A | HOH655 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 304 |
| Chain | Residue |
| A | ASP18 |
| A | MG301 |
| A | HOH435 |
| A | HOH440 |
| A | HOH595 |
| C | DT8 |
| C | DT9 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | ASP18 |
| B | GLU20 |
| B | ASP200 |
| B | MG303 |
| D | DT6 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CO B 302 |
| Chain | Residue |
| A | HOH637 |
| B | PRO79 |
| B | GLY80 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 303 |
| Chain | Residue |
| B | ASP18 |
| B | MG301 |
| B | HOH431 |
| B | HOH446 |
| B | HOH551 |
| D | DC5 |
| D | DT6 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17293595","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780819","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22071149","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9NSU2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
