8HCC
Crystal structure of mTREX1-RNA product complex (AMP)
Summary for 8HCC
| Entry DOI | 10.2210/pdb8hcc/pdb |
| Descriptor | Three-prime repair exonuclease 1, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
| Functional Keywords | trex1, deddh exonuclease, dnase, rnase, amp, hydrolase |
| Biological source | Mus musculus (house mouse) |
| Total number of polymer chains | 4 |
| Total formula weight | 121205.88 |
| Authors | Hsiao, Y.Y.,Huang, K.W.,Wu, C.Y. (deposition date: 2022-11-01, release date: 2023-11-08, Last modification date: 2023-12-13) |
| Primary citation | Huang, K.W.,Wu, C.Y.,Toh, S.I.,Liu, T.C.,Tu, C.I.,Lin, Y.H.,Cheng, A.J.,Kao, Y.T.,Chu, J.W.,Hsiao, Y.Y. Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51:11927-11940, 2023 Cited by PubMed: 37870446DOI: 10.1093/nar/gkad910 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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