8HCC
Crystal structure of mTREX1-RNA product complex (AMP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Three-prime repair exonuclease 1 | polymer | 276 | 29876.9 | 4 | UniProt (Q91XB0) | Mus musculus (house mouse) | 3'-5' exonuclease TREX1,DNase III |
| 2 | E, I, N, R (A, B, C, D) | ADENOSINE MONOPHOSPHATE | non-polymer | 347.2 | 4 | Chemie (AMP) PubChem (16397049) PubChem (16760266) PubChem (224) PubChem (40467049) PubChem (40469468) PubChem (34768) PubChem (44348067) PubChem (83862) PubChem (45358029) PubChem (46874558) PubChem (40459109) PubChem (57358045) PubChem (57879893) PubChem (57879902) PubChem (46875232) PubChem (446048) PubChem (515384) PubChem (638042) PubChem (177678969) PubChem (6083) PubChem (1549371) PubChem (5316444) PubChem (92144436) PubChem (5742864) PubChem (122197642) PubChem (12358354) PubChem (12163610) PubChem (12358355) PubChem (162290139) PubChem (162946266) PubChem (171699505) | |||
| 3 | F, G, J, K, O... (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) PubChem (888) | |||
| 4 | H, L, M, Q, U (A, B, C, D) | SODIUM ION | non-polymer | 23.0 | 5 | Chemie (NA) PubChem (923) | |||
| 5 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 648 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 242 (UniProt: Q91XB0)
| PDB | External Database | Details |
|---|---|---|
| Met -33 | - | initiating methionine |
| Gly -32 | - | expression tag |
| Ser -31 | - | expression tag |
| Ser -30 | - | expression tag |
| His -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| Ser -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Gly -21 | - | expression tag |
| Leu -20 | - | expression tag |
| Val -19 | - | expression tag |
| Pro -18 | - | expression tag |
| Arg -17 | - | expression tag |
| Gly -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| Met -13 | - | expression tag |
| Ala -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Met -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Gln -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Met -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119507.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1698.3 | |
| All* | Total formula weight | 121205.9 |
