8HCC

Crystal structure of mTREX1-RNA product complex (AMP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Three-prime repair exonuclease 1	polymer	276	29876.9	4	UniProt (Q91XB0) In PDB	Mus musculus (house mouse)	3'-5' exonuclease TREX1,DNase III
2	A, B, C, D	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	4	Chemie (AMP)
3	A, B, C, D	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
4	A, B, C, D	SODIUM ION	non-polymer		23.0	5	Chemie (NA)
5		water	water		18.0	648	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 242 (UniProt: Q91XB0)

PDB	External Database	Details
Met -33	-	initiating methionine
Gly -32	-	expression tag
Ser -31	-	expression tag
Ser -30	-	expression tag
His -29	-	expression tag
His -28	-	expression tag
His -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
Ser -23	-	expression tag
Ser -22	-	expression tag
Gly -21	-	expression tag
Leu -20	-	expression tag
Val -19	-	expression tag
Pro -18	-	expression tag
Arg -17	-	expression tag
Gly -16	-	expression tag
Ser -15	-	expression tag
His -14	-	expression tag
Met -13	-	expression tag
Ala -12	-	expression tag
Ser -11	-	expression tag
Met -10	-	expression tag
Thr -9	-	expression tag
Gly -8	-	expression tag
Gly -7	-	expression tag
Gln -6	-	expression tag
Gln -5	-	expression tag
Met -4	-	expression tag
Gly -3	-	expression tag
Arg -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	119507.6
Non-Polymers*	Number of molecules	17
	Total formula weight	1698.3
All*	Total formula weight	121205.9

*Water molecules are not included.