5YWV

Crystal structure of TREX1 in complex with a inosine contained ssDNA

Summary for 5YWV

Entry DOI	10.2210/pdb5ywv/pdb
Descriptor	Three-prime repair exonuclease 1, INOSINE CONTAINED SSDNA, MAGNESIUM ION, ... (7 entities in total)
Functional Keywords	exonuclease, deddh family, protein-dna complex, dna binding protein-dna complex, dna binding protein/dna
Biological source	Mus musculus (Mouse) More
Cellular location	Nucleus: Q91XB0
Total number of polymer chains	4
Total formula weight	60697.01
Authors	Hsiao, Y.Y. (deposition date: 2017-11-30, release date: 2018-05-23, Last modification date: 2023-11-22)
Primary citation	Huang, K.W.,Liu, T.C.,Liang, R.Y.,Chu, L.Y.,Cheng, H.L.,Chu, J.W.,Hsiao, Y.Y. Structural basis for overhang excision and terminal unwinding of DNA duplexes by TREX1 PLoS Biol., 16:e2005653-e2005653, 2018 Cited by PubMed: 29734329 DOI: 10.1371/journal.pbio.2005653 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation