5YWV
Crystal structure of TREX1 in complex with a inosine contained ssDNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Three-prime repair exonuclease 1 | polymer | 259 | 27987.8 | 2 | UniProt (Q91XB0) | Mus musculus (Mouse) | 3'-5' exonuclease TREX1,DNase III |
| 2 | C, D (C, D) | INOSINE CONTAINED SSDNA | polymer | 7 | 2137.4 | 2 | Homo sapiens | ||
| 3 | E, H, I, N (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F, K, L, M (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | J (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 7 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 242 (UniProt: Q91XB0)
| PDB | External Database | Details |
|---|---|---|
| Gly -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| Met -13 | - | expression tag |
| Ala -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Met -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Gly -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Gln -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Met -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 60250.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 446.5 | |
| All* | Total formula weight | 60697.0 |
