5YWV
Crystal structure of TREX1 in complex with a inosine contained ssDNA
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 301 |
| Chain | Residue |
| A | ASP18 |
| A | GLU20 |
| A | ASP200 |
| C | DG7 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NA A 302 |
| Chain | Residue |
| A | LYS211 |
| A | GLN213 |
| A | ALA214 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | THR184 |
| A | TRP188 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 304 |
| Chain | Residue |
| A | ASP18 |
| A | HOH418 |
| A | HOH438 |
| C | DI6 |
| C | DG7 |
| C | HOH210 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | ASP18 |
| B | GLU20 |
| B | HIS195 |
| B | ASP200 |
| D | DG7 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue MES B 302 |
| Chain | Residue |
| A | PRO56 |
| A | VAL57 |
| A | GLN189 |
| B | ASP148 |
| B | GLY149 |
| B | PRO225 |
| B | SER227 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 303 |
| Chain | Residue |
| B | GLY23 |
| B | LEU24 |
| D | DG7 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue NA B 304 |
| Chain | Residue |
| B | LYS211 |
| B | PRO212 |
| B | GLN213 |
| B | ALA214 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue NA B 305 |
| Chain | Residue |
| B | LEU24 |
| B | PRO25 |
| B | SER26 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 306 |
| Chain | Residue |
| B | ASP18 |
| B | HOH418 |
| B | HOH437 |
| D | DI6 |
| D | DG7 |
| D | HOH204 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17293595","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17355961","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18780819","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22071149","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q9NSU2","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
