8HCD

Crystal structure of mTREX1-DNA product complex (dNMP)

Summary for 8HCD

Entry DOI	10.2210/pdb8hcd/pdb
Related	8HCC
Descriptor	Three-prime repair exonuclease 1, MAGNESIUM ION, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, ... (6 entities in total)
Functional Keywords	trex1, deddh exonuclease, dnase, rnase, dcmp, dgmp, hydrolase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	4
Total formula weight	121029.79
Authors	Hsiao, Y.Y.,Huang, K.W.,Wu, C.Y. (deposition date: 2022-11-01, release date: 2023-11-08, Last modification date: 2023-12-13)
Primary citation	Huang, K.W.,Wu, C.Y.,Toh, S.I.,Liu, T.C.,Tu, C.I.,Lin, Y.H.,Cheng, A.J.,Kao, Y.T.,Chu, J.W.,Hsiao, Y.Y. Molecular insight into the specific enzymatic properties of TREX1 revealing the diverse functions in processing RNA and DNA/RNA hybrids. Nucleic Acids Res., 51:11927-11940, 2023 Cited by PubMed: 37870446 DOI: 10.1093/nar/gkad910 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation