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8HCD

Crystal structure of mTREX1-DNA product complex (dNMP)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(B, C, D, E)
Three-prime repair exonuclease 1polymer27629876.94UniProt (Q91XB0)Mus musculus (house mouse)3'-5' exonuclease TREX1,DNase III
2E, G, I, J, L...
(B, C, D, E)
MAGNESIUM IONnon-polymer24.38Chemie (MG)
3F, K, N
(B, D, E)
2'-DEOXYCYTIDINE-5'-MONOPHOSPHATEnon-polymer307.23Chemie (DCM)
4H
(C)
2'-DEOXYGUANOSINE-5'-MONOPHOSPHATEnon-polymer347.21Chemie (DGP)
5Q
(E)
COBALT (II) IONnon-polymer58.91Chemie (CO)
6R, S, T, U
(B, C, D, E)
waterwater18.0784Chemie (HOH)
Sequence modifications
B, C, D, E: 1 - 242 (UniProt: Q91XB0)
PDBExternal DatabaseDetails
Met -33-initiating methionine
Gly -32-expression tag
Ser -31-expression tag
Ser -30-expression tag
His -29-expression tag
His -28-expression tag
His -27-expression tag
His -26-expression tag
His -25-expression tag
His -24-expression tag
Ser -23-expression tag
Ser -22-expression tag
Gly -21-expression tag
Leu -20-expression tag
Val -19-expression tag
Pro -18-expression tag
Arg -17-expression tag
Gly -16-expression tag
Ser -15-expression tag
His -14-expression tag
Met -13-expression tag
Ala -12-expression tag
Ser -11-expression tag
Met -10-expression tag
Thr -9-expression tag
Gly -8-expression tag
Gly -7-expression tag
Gln -6-expression tag
Gln -5-expression tag
Met -4-expression tag
Gly -3-expression tag
Arg -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight119507.6
Non-Polymers*Number of molecules13
Total formula weight1522.2
All*Total formula weight121029.8
*Water molecules are not included.

239149

數據於2025-07-23公開中

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