7V3C
Crystal structure of NP exonuclease C409A-PCMB complex
Summary for 7V3C
Entry DOI | 10.2210/pdb7v3c/pdb |
Related | 7V37 7V38 7V39 7V3A 7V3B |
Descriptor | Nucleoprotein, ZINC ION, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | deddh exonuclease, np exonuclease, anti-viral drug, pcmps, pcmb, viral protein |
Biological source | Lassa virus (strain Mouse/Sierra Leone/Josiah/1976) (LASV) |
Total number of polymer chains | 2 |
Total formula weight | 55841.29 |
Authors | Hsiao, Y.Y.,Huang, K.W. (deposition date: 2021-08-10, release date: 2021-12-15, Last modification date: 2023-11-29) |
Primary citation | Huang, K.W.,Chen, J.W.,Hua, T.Y.,Chu, Y.Y.,Chiu, T.Y.,Liu, J.Y.,Tu, C.I.,Hsu, K.C.,Kao, Y.T.,Chu, J.W.,Hsiao, Y.Y. Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites. Jacs Au, 1:2315-2327, 2021 Cited by PubMed: 34977900DOI: 10.1021/jacsau.1c00420 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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