4LUN
 
 | | Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons | | 分子名称: | CHLORIDE ION, Nonsense-mediated mRNA decay protein 2 | | 著者 | Fourati, Z, Roy, B, Millan, C, Courreux, P.D, Kervestin, S, van Tilbeurgh, H, He, F, Uson, I, Jacobson, A, Graille, M. | | 登録日 | 2013-07-25 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | | 主引用文献 | A highly conserved region essential for NMD in the Upf2 N-terminal domain.
J.Mol.Biol., 426, 2014
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4QH4
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4QH1
 | | The GLIC pentameric Ligand-Gated Ion Channel (wild-type) in complex with bromoacetate | | 分子名称: | BROMIDE ION, Proton-gated ion channel, SODIUM ION, ... | | 著者 | Fourati, Z, Delarue, M, Sauguet, L. | | 登録日 | 2014-05-26 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
Acta Crystallogr.,Sect.D, 2015
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4QH5
 | | The GLIC pentameric Ligand-Gated Ion Channel (wild-type) crystallized in phosphate buffer | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Fourati, Z, Delarue, M, Sauguet, L. | | 登録日 | 2014-05-26 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural characterization of potential modulation sites in the extracellular domain of the prokaryotic pentameric proton-gated ion channel GLIC
Acta Crystallogr.,Sect.D, 2015
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5L4E
 | | X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with thiopental | | 分子名称: | 5-ethyl-5-[(2R)-pentan-2-yl]-2-thioxodihydropyrimidine-4,6(1H,5H)-dione, CHLORIDE ION, DODECANE, ... | | 著者 | Fourati, Z, Ruza, R.R, Delarue, M. | | 登録日 | 2016-05-25 | | 公開日 | 2016-12-21 | | 最終更新日 | 2017-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.
J. Biol. Chem., 292, 2017
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5L4H
 | | X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with 5-(2-BROMO-ETHYL)-5-ETHYL-PYRIMIDINE-2,4,6-TRIONE (brominated barbiturate) | | 分子名称: | 5-(2-bromoethyl)-5-ethyl-1,3-diazinane-2,4,6-trione, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Fourati, Z, Ruza, R.R, Delarue, M. | | 登録日 | 2016-05-25 | | 公開日 | 2016-12-21 | | 最終更新日 | 2017-02-15 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.
J. Biol. Chem., 292, 2017
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5MUO
 | | X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol | | 分子名称: | 2,6-BIS(1-METHYLETHYL)PHENOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Fourati, Z, Ruza, R.R, Delarue, M. | | 登録日 | 2017-01-13 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
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5MVM
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5MVN
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5MZQ
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5MZR
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5MZT
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6EMX
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6HJB
 | | Xray structure of GLIC in complex with malonate | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Fourati, Z, Delarue, M. | | 登録日 | 2018-09-03 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
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6HJ3
 | | Xray structure of GLIC in complex with fumarate | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Fourati, Z, Delarue, M. | | 登録日 | 2018-08-31 | | 公開日 | 2019-09-11 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
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6HJI
 | | Xray structure of GLIC in complex with crotonate | | 分子名称: | BUTENOIC ACID, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Fourati, Z, Delarue, M. | | 登録日 | 2018-09-03 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
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6HJZ
 | | Xray structure of GLIC in complex with succinate | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Fourati, Z, Delarue, M. | | 登録日 | 2018-09-04 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
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6HJA
 | | Xray structure of GLIC in complex with glutarate | | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECANE, ... | | 著者 | Fourati, Z, Delarue, M. | | 登録日 | 2018-09-03 | | 公開日 | 2019-09-18 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
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6HPP
 | | X-ray structure of GLIC in complex with propionate | | 分子名称: | CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, PROPANOIC ACID, ... | | 著者 | Fourati, Z, Delarue, M. | | 登録日 | 2018-09-21 | | 公開日 | 2019-10-09 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
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5IUX
 | | GLIC-V135C bimane labelled X-ray structure | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,3,5,6-tetramethyl-1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione, ACETATE ION, ... | | 著者 | Fourati, Z, Menny, A, Delarue, M. | | 登録日 | 2016-03-18 | | 公開日 | 2017-03-29 | | 最終更新日 | 2019-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Identification of a pre-active conformation of a pentameric channel receptor.
Elife, 6, 2017
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5L47
 | | X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with cyanoselenobarbital (seleniated barbiturate) | | 分子名称: | 2-[5-ethyl-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-yl]ethyl selenocyanate, ACETATE ION, CHLORIDE ION, ... | | 著者 | Reinholds Ruza, R, Fourati, Z, Delarue, M. | | 登録日 | 2016-05-25 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.
J. Biol. Chem., 292, 2017
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5MUR
 | | X-ray structure of the F14'A mutant of GLIC in complex with propofol | | 分子名称: | 2,6-BIS(1-METHYLETHYL)PHENOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Sauguet, L, Fourati, Z, Delarue, M. | | 登録日 | 2017-01-13 | | 公開日 | 2018-02-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.
Cell Rep, 23, 2018
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5NJY
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5NKJ
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4ZZB
 | | The GLIC pentameric Ligand-Gated Ion Channel Locally-closed form complexed to xenon | | 分子名称: | ACETATE ION, CHLORIDE ION, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Sauguet, L, Fourati, Z, Prange, T, Delarue, M, Colloc'h, N. | | 登録日 | 2015-05-22 | | 公開日 | 2016-03-02 | | 最終更新日 | 2018-11-21 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structural Basis for Xenon Inhibition in a Cationic Pentameric Ligand-Gated Ion Channel.
Plos One, 11, 2016
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