5MZQ

X-ray structure of the M205W mutant of GLIC in complex with bromoform

Summary for 5MZQ

• Entry DOI: 10.2210/pdb5mzq/pdb
• Descriptor: Proton-gated ion channel, ACETATE ION, 1,2-DIOCTANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (9 entities in total)
• Functional Keywords: membrane protein, transport protein
• Biological source: Gloeobacter violaceus (strain PCC 7421)
• Total number of polymer chains: 5
• Total formula weight: 196169.92

Authors

Fourati, Z.,Delarue, M. (deposition date: 2017-02-01, release date: 2018-02-28, Last modification date: 2019-10-16)

• Primary citation: Fourati, Z.,Howard, R.J.,Heusser, S.A.,Hu, H.,Ruza, R.R.,Sauguet, L.,Lindahl, E.,Delarue, M.; Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.; Cell Rep, 23:993-1004, 2018; PubMed: 29694907; DOI: 10.1016/j.celrep.2018.03.108

Experimental method

X-RAY DIFFRACTION (2.8 Å)