5MVN

X-ray structure of the M205W mutant of GLIC in complex with propofol

Summary for 5MVN

• Entry DOI: 10.2210/pdb5mvn/pdb
• Descriptor: Proton-gated ion channel, ACETATE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... (8 entities in total)
• Functional Keywords: membrane protein, transport protein
• Biological source: Gloeobacter violaceus PCC 7421
• Total number of polymer chains: 5
• Total formula weight: 195759.51

Authors

Fourati, Z.,Delarue, M. (deposition date: 2017-01-16, release date: 2018-02-14, Last modification date: 2024-01-17)

• Primary citation: Fourati, Z.,Howard, R.J.,Heusser, S.A.,Hu, H.,Ruza, R.R.,Sauguet, L.,Lindahl, E.,Delarue, M.; Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.; Cell Rep, 23:993-1004, 2018; PubMed: 29694907; DOI: 10.1016/j.celrep.2018.03.108

Experimental method

X-RAY DIFFRACTION (3.49 Å)