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4LUN

Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons

Summary for 4LUN
Entry DOI10.2210/pdb4lun/pdb
DescriptorNonsense-mediated mRNA decay protein 2, CHLORIDE ION (3 entities in total)
Functional Keywordsheat-repeat, mrna decay, rna binding protein
Biological sourceSaccharomyces cerevisiae (Baker's yeast)
Cellular locationCytoplasm : P38798
Total number of polymer chains1
Total formula weight36673.59
Authors
Fourati, Z.,Roy, B.,Millan, C.,Courreux, P.D.,Kervestin, S.,van Tilbeurgh, H.,He, F.,Uson, I.,Jacobson, A.,Graille, M. (deposition date: 2013-07-25, release date: 2014-07-30, Last modification date: 2024-02-28)
Primary citationFourati, Z.,Roy, B.,Millan, C.,Coureux, P.D.,Kervestin, S.,van Tilbeurgh, H.,He, F.,Uson, I.,Jacobson, A.,Graille, M.
A highly conserved region essential for NMD in the Upf2 N-terminal domain.
J.Mol.Biol., 426:3689-3702, 2014
Cited by
PubMed: 25277656
DOI: 10.1016/j.jmb.2014.09.015
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.641 Å)
Structure validation

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