5MUO

X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol

Summary for 5MUO

• Entry DOI: 10.2210/pdb5muo/pdb
• Related: 3TLS 3TLT 3TLU 3TLW
• Descriptor: Proton-gated ion channel, DODECYL-BETA-D-MALTOSIDE, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: membrane protein, transport protein
• Biological source: Gloeobacter violaceus
• Total number of polymer chains: 5
• Total formula weight: 183731.94

Authors

Fourati, Z.,Ruza, R.R.,Delarue, M. (deposition date: 2017-01-13, release date: 2018-02-14, Last modification date: 2024-01-17)

• Primary citation: Fourati, Z.,Howard, R.J.,Heusser, S.A.,Hu, H.,Ruza, R.R.,Sauguet, L.,Lindahl, E.,Delarue, M.; Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels.; Cell Rep, 23:993-1004, 2018; PubMed: 29694907; DOI: 10.1016/j.celrep.2018.03.108

Experimental method

X-RAY DIFFRACTION (3.19 Å)