5MUO
X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E | Proton-gated ion channel | polymer | 321 | 36525.9 | 5 | UniProt (Q7NDN8) Pfam (PF02931) In PDB | Gloeobacter violaceus | GLIC,Ligand-gated ion channel,LGIC |
2 | A | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
3 | A, B, C, D, E | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
4 | A, B, D, E | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
5 | D | 2,6-BIS(1-METHYLETHYL)PHENOL | non-polymer | 178.3 | 1 | Chemie (PFL) | |||
6 | water | water | 18.0 | 76 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2 - 317 (UniProt: Q7NDN8)
PDB | External Database | Details |
---|---|---|
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Ala -1 | - | expression tag |
Ala 0 | - | expression tag |
Ala 1 | - | expression tag |
Ser 27 | Cys 69 | conflict |
Cys 33 | Lys 75 | conflict |
Cys 246 | Leu 288 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 182629.6 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 1102.3 | |
All* | Total formula weight | 183731.9 |