5L47

X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with cyanoselenobarbital (seleniated barbiturate)

Summary for 5L47

• Entry DOI: 10.2210/pdb5l47/pdb
• Descriptor: Proton-gated ion channel, CHLORIDE ION, ACETATE ION, ... (7 entities in total)
• Functional Keywords: membrane protein, transport protein
• Biological source: Gloeobacter
• Cellular location: Cell inner membrane ; Multi- pass membrane protein : Q7NDN8
• Total number of polymer chains: 5
• Total formula weight: 182150.97

Authors

Reinholds Ruza, R.,Fourati, Z.,Delarue, M. (deposition date: 2016-05-25, release date: 2016-12-21, Last modification date: 2024-01-10)

• Primary citation: Fourati, Z.,Ruza, R.R.,Laverty, D.,Drege, E.,Delarue-Cochin, S.,Joseph, D.,Koehl, P.,Smart, T.,Delarue, M.; Barbiturates Bind in the GLIC Ion Channel Pore and Cause Inhibition by Stabilizing a Closed State.; J. Biol. Chem., 292:1550-1558, 2017; PubMed: 27986812; DOI: 10.1074/jbc.M116.766964

Experimental method

X-RAY DIFFRACTION (3.3 Å)