5L47
X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with cyanoselenobarbital (seleniated barbiturate)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Proton-gated ion channel | polymer | 317 | 36225.6 | 5 | UniProt (Q7NDN8) Pfam (PF02931) | Gloeobacter | GLIC,Ligand-gated ion channel,LGIC |
| 2 | F, I, L, P, S (A, B, C, D, E) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 3 | G, K, M, Q, T (A, B, C, D, E) | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
| 4 | H, N, R, U (A, C, D, E) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | J (B) | 2-[5-ethyl-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-yl]ethyl selenocyanate | non-polymer | 288.2 | 1 | Chemie (6JA) | |||
| 6 | O (D) | DODECANE | non-polymer | 170.3 | 1 | Chemie (D12) | |||
| 7 | V, W, X, Y, Z (A, B, C, D, E) | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 317 (UniProt: Q7NDN8)
| PDB | External Database | Details |
|---|---|---|
| Ser 27 | Cys 69 | conflict |
| Cys 33 | Lys 75 | conflict |
| Cys 246 | Leu 288 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181128.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1022.9 | |
| All* | Total formula weight | 182151.0 |
