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2OGM
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BU of 2ogm by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-571519
分子名称: (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE, 23S ribosomal RNA, 50S ribosomal protein L3
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGN
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BU of 2ogn by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-280080
分子名称: (3AS,4R,5S,6S,8R,9R,9AR,10R)-5-HYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROPANOCYCLOPENTA[8]ANNULEN-8-YL (PIPERIDIN-4-YLTHIO)ACETATE, 23S ribosomal RNA, 50S ribosomal protein L3
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.56 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2OGO
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BU of 2ogo by Molmil
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative retapamulin (SB-275833)
分子名称: 23S ribosomal RNA, 50S ribosomal protein L3, Retapamulin
著者Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A.
登録日2007-01-07
公開日2007-05-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.66 Å)
主引用文献Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity.
Proc.Natl.Acad.Sci.Usa, 104, 2007
2W84
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BU of 2w84 by Molmil
Structure of Pex14 in complex with Pex5
分子名称: PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR
著者Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M.
登録日2009-01-09
公開日2009-02-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
EMBO J., 28, 2009
2W85
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BU of 2w85 by Molmil
Structure of Pex14 in complex with Pex19
分子名称: PEROXIN-19, PEROXISOMAL MEMBRANE ANCHOR PROTEIN PEX14
著者Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M.
登録日2009-01-09
公開日2009-02-17
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Competitive Interactions of Pex14 with the Import Receptors Pex5 and Pex19.
Embo J., 28, 2009
5NE0
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BU of 5ne0 by Molmil
Room temperature in-situ structure of hen egg-white lysozyme from crystals enclosed between ultrathin silicon nitride membranes
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Martiel, I, Opara, N, Arnold, S.A, Braun, T, Stahlberg, H, Makita, M, David, C, Padeste, C.
登録日2017-03-09
公開日2017-06-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers.
J.Appl.Crystallogr., 50, 2017
4X3B
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BU of 4x3b by Molmil
A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering
分子名称: CHLORIDE ION, Lysozyme C, SODIUM ION
著者Roedig, P, Vartiainen, I, Duman, R, Panneerselvam, S, Stuebe, N, Lorbeer, O, Warmer, M, Sutton, G, Stuart, D.I, Weckert, E, David, C, Wagner, A, Meents, A.
登録日2014-11-28
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering.
Sci Rep, 5, 2015
4X35
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BU of 4x35 by Molmil
A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Roedig, P, Vartiainen, I, Duman, R, Panneerselvam, S, Stuebe, N, Lorbeer, O, Warmer, M, Sutton, G, Stuart, D.I, Weckert, E, David, C, Wagner, A, Meents, A.
登録日2014-11-27
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A micro-patterned silicon chip as sample holder for macromolecular crystallography experiments with minimal background scattering.
Sci Rep, 5, 2015
5FB6
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BU of 5fb6 by Molmil
Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering
分子名称: Insulin Chain A, Insulin Chain B
著者Roedig, P, Duman, R, Sanchez-Weatherby, J, Vartiainen, I, Burkhardt, A, Warmer, M, David, C, Wagner, A, Meents, A.
登録日2015-12-14
公開日2016-06-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Room-temperature macromolecular crystallography using a micro-patterned silicon chip with minimal background scattering.
J.Appl.Crystallogr., 49, 2016
5MQW
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BU of 5mqw by Molmil
High-speed fixed-target serial virus crystallography
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A.
登録日2016-12-21
公開日2017-06-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
5OSN
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BU of 5osn by Molmil
Crystal Structure of Bovine Enterovirus 2 determined with Serial Femtosecond X-ray Crystallography
分子名称: Capsid protein, GLUTAMIC ACID, POTASSIUM ION, ...
著者Roedig, P, Ginn, H.M, Pakendorf, T, Sutton, G, Harlos, K, Walter, T.S, Meyer, J, Fischer, P, Duman, R, Vartiainen, I, Reime, B, Warmer, M, Brewster, A.S, Young, I.D, Michels-Clark, T, Sauter, N.K, Kotecha, A, Kelly, J, Rowlands, D.J, Sikorsky, M, Nelson, S, Damiani, D.S, Alonso-Mori, R, Ren, J, Fry, E.E, David, C, Stuart, D.I, Wagner, A, Meents, A.
登録日2017-08-17
公開日2017-08-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献High-speed fixed-target serial virus crystallography.
Nat. Methods, 14, 2017
6V3X
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BU of 6v3x by Molmil
Crystal structure of EED in complex with PALI1-K1241me3 peptide
分子名称: PALI1 peptide, Polycomb protein EED
著者Zhang, Q, Davidovich, C.
登録日2019-11-26
公開日2021-05-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
6V3Y
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BU of 6v3y by Molmil
Crystal structure of EED in complex with PALI1-K1219me3 peptide
分子名称: PALI1 peptide, Polycomb protein EED
著者Zhang, Q, Davidovich, C.
登録日2019-11-26
公開日2021-05-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis.
Nat Commun, 12, 2021
3FWO
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BU of 3fwo by Molmil
The large ribosomal subunit from Deinococcus radiodurans complexed with Methymycin
分子名称: (3R,4S,5S,7R,9E,11S,12R)-12-ethyl-11-hydroxy-3,5,7,11-tetramethyl-2,8-dioxooxacyclododec-9-en-4-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 23S RIBOSOMAL RNA, 5S RIBOSOMAL RNA
著者Auerbach, T, Mermershtain, I, Bashan, A, Davidovich, C, Rozenberg, H, Sherman, D.H, Yonath, A.
登録日2009-01-19
公開日2010-01-19
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Structural basis for the antibacterial activity of the 12-membered-ring mono-sugar macrolide methymycin
Biotechnologia, 1, 2009
3JQ4
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BU of 3jq4 by Molmil
The structure of the complex of the large ribosomal subunit from D. Radiodurans with the antibiotic lankacidin
分子名称: 23S ribosomal RNA, 5S ribosomal RNA, N-[(1S,2R,3E,5E,7S,9E,11E,13S,15R,19R)-7,13-dihydroxy-1,4,10,19-tetramethyl-17,18-dioxo-16-oxabicyclo[13.2.2]nonadeca-3,5,9,11-tetraen-2-yl]-2-oxopropanamide
著者Auerbach-Nevo, T, Mermershtain, I, Davidovich, C, Bashan, A, Rozenberg, H, Yonath, A.
登録日2009-09-06
公開日2010-09-08
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.52 Å)
主引用文献The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics
Proc.Natl.Acad.Sci.USA, 107, 2010
1DRB
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BU of 1drb by Molmil
CRYSTAL STRUCTURE OF UNLIGANDED ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE. LIGAND-INDUCED CONFORMATIONAL CHANGES AND COOPERATIVITY IN BINDING
分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
著者David, C, Kraut, J.
登録日1991-11-06
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Crystal structure of unliganded Escherichia coli dihydrofolate reductase. Ligand-induced conformational changes and cooperativity in binding.
Biochemistry, 30, 1991
5M7M
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BU of 5m7m by Molmil
Novel Imidazo[1,2-a]pyridine Derivatives with Potent Autotaxin/ENPP2 Inhibitor Activity
分子名称: CHLORIDE ION, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, IODIDE ION, ...
著者Wolhkoning, A, Fleury, D, Leonard, P, Triballeau, N, Mollat, P, Vercheval, L.
登録日2016-10-28
公開日2017-08-30
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors.
J. Med. Chem., 60, 2017
6R95
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BU of 6r95 by Molmil
The solution NMR structure of cis-dicarba-brevinin-1BYa in 33% trifluoroethanol
分子名称: Brevinin-1BYa
著者Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
登録日2019-04-02
公開日2019-09-25
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
6R96
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BU of 6r96 by Molmil
The solution NMR structure of cis-dicarba-brevinin-1BYa in sodium dodecyl sulphate micelles
分子名称: Brevinin-1BYa
著者Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
登録日2019-04-02
公開日2019-09-25
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Insights into conformation and membrane interactions of the acyclic and dicarba-bridged brevinin-1BYa antimicrobial peptides.
Eur.Biophys.J., 48, 2019
4WFN
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BU of 4wfn by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin
分子名称: 23S ribosomal RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
登録日2014-09-16
公開日2015-12-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.54 Å)
主引用文献The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
4U67
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BU of 4u67 by Molmil
Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22
分子名称: 23s RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ...
著者Wekselman, I, Zimmerman, E, Rozenberg, H, Bashan, A, Yonath, A.
登録日2014-07-28
公開日2015-08-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
Structure, 25, 2017
7PKO
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BU of 7pko by Molmil
CryoEM structure of Rotavirus NSP2
分子名称: Non-structural protein 2
著者Bravo, J.P.K, Borodavka, A.
登録日2021-08-26
公開日2021-09-29
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PKP
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BU of 7pkp by Molmil
NSP2 RNP complex
分子名称: Non-structural protein 2
著者Bravo, J.P.K, Borodavka, A.
登録日2021-08-26
公開日2021-09-29
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis of rotavirus RNA chaperone displacement and RNA annealing.
Proc.Natl.Acad.Sci.USA, 118, 2021
6G4U
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BU of 6g4u by Molmil
The solution NMR structure of brevinin-1BYa in dodecylphosphocholine micelles
分子名称: Brevinin-1BYa
著者Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
登録日2018-03-28
公開日2019-10-16
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments.
J.Pept.Sci., 25, 2019
6G4I
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BU of 6g4i by Molmil
The solution NMR structure of brevinin-1BYa in 33% trifluoroethanol
分子名称: Brevinin-1BYa
著者Timmons, P.B, O'Flynn, D.P, Conlon, J.M, Hewage, C.M.
登録日2018-03-27
公開日2019-10-09
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and positional studies of the antimicrobial peptide brevinin-1BYa in membrane-mimetic environments.
J.Pept.Sci., 25, 2019

 

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