2OGO
The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative retapamulin (SB-275833)
Summary for 2OGO
| Entry DOI | 10.2210/pdb2ogo/pdb |
| Descriptor | 23S ribosomal RNA, 50S ribosomal protein L3, Retapamulin (3 entities in total) |
| Functional Keywords | retapamulin, sb-275833, pleuromutilin, ptc, peptidyl transferase center, ribosome, antibiotic |
| Biological source | Deinococcus radiodurans More |
| Total number of polymer chains | 2 |
| Total formula weight | 956399.91 |
| Authors | Davidovich, C.,Bashan, A.,Auerbach-Nevo, T.,Yonath, A. (deposition date: 2007-01-07, release date: 2007-05-01, Last modification date: 2023-12-27) |
| Primary citation | Davidovich, C.,Bashan, A.,Auerbach-Nevo, T.,Yaggie, R.D.,Gontarek, R.R.,Yonath, A. Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity. Proc.Natl.Acad.Sci.Usa, 104:4291-4296, 2007 Cited by PubMed: 17360517DOI: 10.1073/pnas.0700041104 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.66 Å) |
Structure validation
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