8C0V
 
 | | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in single seam state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C. | | Deposit date: | 2022-12-19 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate.
Nat Commun, 14, 2023
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8C0W
 | | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate in twin seam state | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Ruettermann, M, Koci, M, Lill, P, Geladas, E.D, Kaschani, F, Klink, B.U, Erdmann, R, Gatsogiannis, C. | | Deposit date: | 2022-12-19 | | Release date: | 2023-10-04 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structure of the peroxisomal Pex1/Pex6 ATPase complex bound to a substrate.
Nat Commun, 14, 2023
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6SPT
 | | High resolution crystal structure of N-terminal domain of PEX14 from Trypanosoma brucei in complex with the fist compound with sub-micromolar trypanocidal activity | | Descriptor: | 5-[(4-methoxynaphthalen-1-yl)methyl]-1-[2-[(2-methyl-1-oxidanyl-propan-2-yl)amino]ethyl]-~{N}-(naphthalen-1-ylmethyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridine-3-carboxamide, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | | Authors: | Napolitano, V, Dawidowski, M, Kalel, V.C, Fino, R, Emmanouilidis, L, Lenhart, D, Ostertag, M, Kaiser, M, Kolonko, M, Schilebs, W, Maser, P, Tetko, I, Hadian, K, Plettenburg, O, Erdmann, R, Sattler, M, Popowicz, G.M, Dubin, G. | | Deposit date: | 2019-09-02 | | Release date: | 2020-01-01 | | Last modified: | 2020-02-05 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure-Activity Relationship in Pyrazolo[4,3-c]pyridines, First Inhibitors of PEX14-PEX5 Protein-Protein Interaction with Trypanocidal Activity.
J.Med.Chem., 63, 2020
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5LNF
 | | Solution NMR structure of farnesylated PEX19, C-terminal domain | | Descriptor: | FARNESYL, Peroxisomal biogenesis factor 19 | | Authors: | Emmanouilidis, L, Schuetz, U, Tripsianes, K, Madl, T, Radke, J, Rucktaeschel, R, Wilmanns, M, Schliebs, W, Erdmann, R, Sattler, M. | | Deposit date: | 2016-08-04 | | Release date: | 2017-03-15 | | Last modified: | 2019-09-11 | | Method: | SOLUTION NMR | | Cite: | Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19.
Nat Commun, 8, 2017
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1NM7
 | | Solution structure of the ScPex13p SH3 domain | | Descriptor: | Peroxisomal Membrane Protein PAS20 | | Authors: | Pires, J.R, Hong, X, Brockmann, C, Volkmer-Engert, R, Schneider-Mergener, J, Oschkinat, H, Erdmann, R. | | Deposit date: | 2003-01-09 | | Release date: | 2003-03-04 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | The ScPex13p SH3 Domain Exposes Two Distinct Binding Sites for Pex5p and Pex14p
J.Mol.Biol., 326, 2003
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2WL8
 | | X-ray crystal structure of Pex19p | | Descriptor: | PEROXISOMAL BIOGENESIS FACTOR 19 | | Authors: | Schueller, N, Holton, S.J, Stanley, W.A, Song, Y.H, Konarev, P, Roessle, M, Erdmann, R, Schliebs, W, Wilmanns, M. | | Deposit date: | 2009-06-22 | | Release date: | 2010-06-23 | | Last modified: | 2019-07-24 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | The Peroxisomal Receptor Pex19P Forms a Helical Mpts Recognition Domain.
Embo J., 29, 2010
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2W84
 | | Structure of Pex14 in complex with Pex5 | | Descriptor: | PEROXISOMAL MEMBRANE PROTEIN PEX14, PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR | | Authors: | Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M. | | Deposit date: | 2009-01-09 | | Release date: | 2009-02-17 | | Last modified: | 2018-01-17 | | Method: | SOLUTION NMR | | Cite: | Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19.
EMBO J., 28, 2009
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2W85
 | | Structure of Pex14 in complex with Pex19 | | Descriptor: | PEROXIN-19, PEROXISOMAL MEMBRANE ANCHOR PROTEIN PEX14 | | Authors: | Neufeld, C, Filipp, F.V, Simon, B, Neuhaus, A, Schueller, N, David, C, Kooshapur, H, Madl, T, Erdmann, R, Schliebs, W, Wilmanns, M, Sattler, M. | | Deposit date: | 2009-01-09 | | Release date: | 2009-02-17 | | Last modified: | 2013-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural Basis for Competitive Interactions of Pex14 with the Import Receptors Pex5 and Pex19.
Embo J., 28, 2009
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