4WFN

Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a three residue insertion in L22 in complex with erythromycin

Summary for 4WFN

• Entry DOI: 10.2210/pdb4wfn/pdb
• Related: 4U67
• Descriptor: 50S ribosomal protein L2, 50S ribosomal protein L17, 50S ribosomal protein L18, ... (30 entities in total)
• Functional Keywords: ribosome, antibiotics, rresistance, erythromycin
• Biological source: Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422); More
• Total number of polymer chains: 28
• Total formula weight: 1348061.60

Authors

Wekselman, I.,Zimmerman, E.,Rozenberg, H.,Bashan, A.,Yonath, A. (deposition date: 2014-09-16, release date: 2015-12-23, Last modification date: 2024-01-10)

• Primary citation: Wekselman, I.,Zimmerman, E.,Davidovich, C.,Belousoff, M.,Matzov, D.,Krupkin, M.,Rozenberg, H.,Bashan, A.,Friedlander, G.,Kjeldgaard, J.,Ingmer, H.,Lindahl, L.,Zengel, J.M.,Yonath, A.; The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.; Structure, 25:1233-1241.e3, 2017; PubMed: 28689968; DOI: 10.1016/j.str.2017.06.004

Experimental method

X-RAY DIFFRACTION (3.54 Å)